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ASCLETIS-B

9.940

+0.4004.19%

Volume:1.70M

Turnover:17.33M

Market Cap:10.46B

PE:-26.86

High:10.600

Open:9.800

Low:9.500

Close:9.540

52wk High:19.860

52wk Low:7.950

Shares:1.05B

HK Float Shares:1.05B

Volume Ratio:2.48

T/O Rate:0.16%

Dividend:- -

Dividend Rate:- -

EPS(LYR):-0.370

ROE:-28.59%

ROA:-20.12%

PB:3.95

PE(LYR):-26.86

PS:9468.77

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Overview Company News Filings

ASCLETIS-B Nears Previous Peak, But Why Are Investors Staying on the Sidelines?

ASCLETIS-B Shares Surge Nearly 5% in Afternoon Trading, Approaching All-Time High as GLP-1 and Amylin Combo Enters Clinical Trials

Analysts Are Optimistic We'll See A Profit From Ascletis Pharma Inc. (HKG:1672)

Simply Wall St.

ASCLETIS-B Maintains Stable Share Base in March; No New Issuance, Public Float Fully Compliant

Bulletin Express

ASCLETIS-B Advances Clinical Development of Fixed-Dose Combination ASC30_39 for Obesity Treatment

BRIEF-Ascletis Announces Fixed-Dose Combination of ASC30, Once-Daily Oral Small Molecule GLP-1R Agonist, and ASC39, Once-Daily Oral Small Molecule Amylin-Selective Amylin Receptor Agonist, for Clinical Development

Ascletis Accelerates Obesity Pipeline with First-in-Class Oral GLP-1/Amylin Fixed-Dose Combo; IND Targeted for Q3 2026

Bulletin Express

Ascletis Pharma Inc - Expects Ind Submission to FDA for Asc30_39 Fdc in Q3 2026

THOMSON REUTERS

Ascletis targets Q3 2026 FDA IND filing for oral obesity combo ASC30_39 tablet

Ascletis Pharma's Loss Widens 20% in 2025; Shares Rise 5%

MT Newswires Live

BRIEF-Ascletis Pharma FY Loss Attributable Rmb359.9 Million

ASCLETIS-B Reports Annual Loss Attributable to Shareholders of 360 Million Yuan, Widening 19.6% Year-on-Year

Ascletis Pharma Inc - FY Loss Attributable RMB359.9 Mln

THOMSON REUTERS

HK Pharma Stocks Gained. CSPC Pharma Up 13%; Lepu Bio Up 7%; Hengrui Pharma And Junshi Bio Up 6%; HBM, Beigene, Sihuan Pharm Up 5%

Tiger Newspress

HK Pharma Stocks Gained. XuanzhuBio Up 9%; Xtalpi, Lepu Bio And Ascletis Up 6%; Akeso Up 5%; Skb Bio Up 4%.

Tiger Newspress

HK Pharma Stocks Gained. Wuxi XDC Up 8%; Wuxi AppTec Up 7%; Transthera And HBM Up 5%; Keymed Bio And Innocare Up 4%; Wuxi Bio And Remegen Up 3%

Tiger Newspress

BRIEF-Ascletis Pharma Expects To Submit IND Application To U.S. FDA For ASC39 In Q3 2026

Ascletis targets Q3 2026 FDA IND filing for ASC39 oral obesity tablets

ASCLETIS-B Selects Oral Amylin Receptor Agonist ASC39 as Clinical Candidate, Demonstrating Eloralintide-Like Selectivity and Efficacy in Preclinical Models

Ascletis Pharma Inc - Expects to Submit Ind Application to U.S. FDA for Asc39 Oral Tablets in Q3 2026

THOMSON REUTERS

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(HKG:1672)","url":"https://stock-news.laohu8.com/highlight/detail?id=2626597860","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626597860?lang=en_us&edition=fundamental","pubTime":"2026-04-09 06:22","pubTimestamp":1775686966,"startTime":"0","endTime":"0","summary":"With the business potentially at an important milestone, we thought we'd take a closer look at Ascletis Pharma Inc.'s...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-1672/ascletis-pharma-shares/news/analysts-are-optimistic-well-see-a-profit-from-ascletis-phar","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-1672/ascletis-pharma-shares/news/analysts-are-optimistic-well-see-a-profit-from-ascletis-phar","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","01672","BK1515","BK1574","BK1161","ASCLF"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188086618","title":"ASCLETIS-B Maintains Stable Share Base in March; No New Issuance, Public Float Fully Compliant","url":"https://stock-news.laohu8.com/highlight/detail?id=1188086618","media":"Bulletin Express","labels":["SGX"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188086618?lang=en_us&edition=fundamental","pubTime":"2026-04-08 12:21","pubTimestamp":1775622107,"startTime":"0","endTime":"0","summary":"Ascletis Pharma Inc. (ASCLETIS-B) released its Monthly Return for Equity Issuers covering March 2026, confirming a month of capital stability with no new share issuance or treasury-share movements....","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"SGX","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1196500897","title":"ASCLETIS-B Advances Clinical Development of Fixed-Dose Combination ASC30_39 for Obesity Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=1196500897","media":"Stock News","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1196500897?lang=en_us&edition=fundamental","pubTime":"2026-04-07 19:36","pubTimestamp":1775561787,"startTime":"0","endTime":"0","summary":"ASCLETIS-B (01672) has announced the selection of ASC30_39 FDC, a fixed-dose combination of once-daily oral small molecule GLP-1 receptor agonist ASC30 and once-daily oral small molecule...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1161","BK4590","01672","GLP","BK1191","01477","BK4144","BK1574","BK1515"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625693214","title":"BRIEF-Ascletis Announces Fixed-Dose Combination of ASC30, Once-Daily Oral Small Molecule GLP-1R Agonist, and ASC39, Once-Daily Oral Small Molecule Amylin-Selective Amylin Receptor Agonist, for Clinical Development","url":"https://stock-news.laohu8.com/highlight/detail?id=2625693214","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625693214?lang=en_us&edition=fundamental","pubTime":"2026-04-07 19:10","pubTimestamp":1775560200,"startTime":"0","endTime":"0","summary":"BRIEF-Ascletis Announces Fixed-Dose Combination of ASC30, Once-Daily Oral Small Molecule GLP-1R Agonist, and ASC39, Once-Daily Oral Small Molecule Amylin-Selective Amylin Receptor Agonist, for Clinica","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nTUA8DXLG9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1574","BK1515","01672","BK1161"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1155993644","title":"Ascletis Accelerates Obesity Pipeline with First-in-Class Oral GLP-1/Amylin Fixed-Dose Combo; IND Targeted for Q3 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=1155993644","media":"Bulletin Express","labels":["productRelease","SGX"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1155993644?lang=en_us&edition=fundamental","pubTime":"2026-04-07 19:05","pubTimestamp":1775559935,"startTime":"0","endTime":"0","summary":"Ascletis Pharma Inc. (Ascletis) has advanced its obesity franchise by selecting a fixed-dose combination (FDC) tablet—ASC30_39—for clinical development. The one-pill, once-daily regimen co-formulates...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease,SGX","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625932323","title":"Ascletis Pharma Inc - Expects Ind Submission to FDA for Asc30_39 Fdc in Q3 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2625932323","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625932323?lang=en_us&edition=fundamental","pubTime":"2026-04-07 19:00","pubTimestamp":1775559600,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nTUA8DXLG9:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK1574","01672","BK1515","BK1161"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625934718","title":"Ascletis targets Q3 2026 FDA IND filing for oral obesity combo ASC30_39 tablet","url":"https://stock-news.laohu8.com/highlight/detail?id=2625934718","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625934718?lang=en_us&edition=fundamental","pubTime":"2026-04-07 18:51","pubTimestamp":1775559108,"startTime":"0","endTime":"0","summary":"Ascletis selected ASC30_39, fixed-dose oral combination of ASC30 and ASC39, for clinical development as a once-daily obesity therapy.Preclinical dosing in dogs showed combination tablets performed in line with each drug given alone, supporting use as a single-pill regimen.Compatibility work indicated formulation stability at room temperature, supporting practical manufacturing and distribution.Ascletis expects to file a US FDA IND for ASC30_39 tablets in Q3 2026.No clinical trial results were presented; development update centered on preclinical findings and planned regulatory filing.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascletis Pharma Inc. published the original content used to generate this news brief via IIS, the Issuer I","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260407:nNDL1GrDdR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1161","BK1515","01672","BK1574"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624656901","title":"Ascletis Pharma's Loss Widens 20% in 2025; Shares Rise 5%","url":"https://stock-news.laohu8.com/highlight/detail?id=2624656901","media":"MT Newswires Live","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624656901?lang=en_us&edition=fundamental","pubTime":"2026-04-01 13:02","pubTimestamp":1775019764,"startTime":"0","endTime":"0","summary":"Ascletis Pharma's  loss attributable to equity shareholders came in at 359.9 million yuan for 2025, widening 20% from 300.9 million yuan a year earlier, according to a Tuesday Hong Kong bourse filing.Shares of the pharmaceutical firm were up over 5% in Wednesday's midday trade.Loss per share came in at 0.3701 yuan, compared with 0.3005 yuan in the prior year.Total income rose 5.2% to 127.4 million yuan from 121.1 million yuan in 2024.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK1161","BK1515","01672","BK1574"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624539658","title":"BRIEF-Ascletis Pharma FY Loss Attributable Rmb359.9 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2624539658","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624539658?lang=en_us&edition=fundamental","pubTime":"2026-04-01 00:45","pubTimestamp":1774975539,"startTime":"0","endTime":"0","summary":"BRIEF-Ascletis Pharma FY Loss Attributable Rmb359.9 MillionMarch 31 (Reuters) - Ascletis Pharma Inc 1672.HK:ASCLETIS PHARMA INC - FY LOSS ATTRIBUTABLE RMB359.9 MILLIONFurther company coverage: 1672.HK ((Reuters.Briefs@thomsonreuters.com;))","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260331:nFWN40J1FZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672","BK1515","BK1161","BK1574"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1165768804","title":"ASCLETIS-B Reports Annual Loss Attributable to Shareholders of 360 Million Yuan, Widening 19.6% Year-on-Year","url":"https://stock-news.laohu8.com/highlight/detail?id=1165768804","media":"Stock News","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1165768804?lang=en_us&edition=fundamental","pubTime":"2026-03-31 22:36","pubTimestamp":1774967774,"startTime":"0","endTime":"0","summary":"ASCLETIS-B (01672) has announced its annual results for the period ended December 31, 2025. The group recorded total revenue of 127 million Chinese yuan, representing a 5.2% increase compared to the...","market":"nz","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1515","BK1191","01672","01477","BK1574","BK1161"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2623580984","title":"Ascletis Pharma Inc - FY Loss Attributable RMB359.9 Mln","url":"https://stock-news.laohu8.com/highlight/detail?id=2623580984","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2623580984?lang=en_us&edition=fundamental","pubTime":"2026-03-31 22:18","pubTimestamp":1774966712,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260331:nFWN40J1FZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK1515","BK1161","BK1574","01672"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1149528263","title":"HK Pharma Stocks Gained. CSPC Pharma Up 13%; Lepu Bio Up 7%; Hengrui Pharma And Junshi Bio Up 6%; HBM, Beigene, Sihuan Pharm Up 5%","url":"https://stock-news.laohu8.com/highlight/detail?id=1149528263","media":"Tiger Newspress","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1149528263?lang=en_us&edition=fundamental","pubTime":"2026-03-27 14:14","pubTimestamp":1774592089,"startTime":"0","endTime":"0","summary":"HK Pharma Stocks Gained. CSPC Pharma Up 13%; Lepu Bio up 7%; Hengrui Pharma and Junshi Bio Up 6%; HBM, Beigene, $Sihuan Pharm(00460)$ Up 5%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["03759","09606","06978","09966","01276","03347","02268","09688","09995","02359","01093","02137","02157","06606","01672","02269"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1148472362","title":"HK Pharma Stocks Gained. XuanzhuBio Up 9%; Xtalpi, Lepu Bio And Ascletis Up 6%; Akeso Up 5%; Skb Bio Up 4%.","url":"https://stock-news.laohu8.com/highlight/detail?id=1148472362","media":"Tiger Newspress","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1148472362?lang=en_us&edition=fundamental","pubTime":"2026-03-26 09:54","pubTimestamp":1774490045,"startTime":"0","endTime":"0","summary":"HK Pharma Stocks Gained. XuanzhuBio up 9%; Xtalpi, Lepu Bio and Ascletis up 6%; Akeso up 5%; Skb Bio up 4%. ","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["09606","03347","09688","02359","02157","02228","02137","02268","02269","01672","03759","06606","09966","09995","06978","02575"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1156264604","title":"HK Pharma Stocks Gained. Wuxi XDC Up 8%; Wuxi AppTec Up 7%; Transthera And HBM Up 5%; Keymed Bio And Innocare Up 4%; Wuxi Bio And Remegen Up 3%","url":"https://stock-news.laohu8.com/highlight/detail?id=1156264604","media":"Tiger Newspress","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1156264604?lang=en_us&edition=fundamental","pubTime":"2026-03-24 09:46","pubTimestamp":1774316807,"startTime":"0","endTime":"0","summary":"HK Pharma Stocks Gained. Wuxi XDC up 8%; Wuxi AppTec up 7%; Transthera and HBM up 5%; Keymed Bio and Innocare up 4%; Wuxi Bio and Remegen up 3%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["09995","02162","09606","02268","02269","03347","06606","01672","02359","09966","06978","03759","02137","09688"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620601422","title":"BRIEF-Ascletis Pharma Expects To Submit IND Application To U.S. FDA For ASC39 In Q3 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2620601422","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620601422?lang=en_us&edition=fundamental","pubTime":"2026-03-17 20:40","pubTimestamp":1773751215,"startTime":"0","endTime":"0","summary":"BRIEF-Ascletis Pharma Expects To Submit IND Application To U.S. FDA For ASC39 In Q3 2026March 17 (Reuters) - Ascletis Pharma Inc 1672.HK:EXPECTS TO SUBMIT IND APPLICATION TO U.S. FDA FOR ASC39 ORAL TABLETS IN Q3 2026Further company coverage: 1672.HK ((Reuters.Briefs@thomsonreuters.com;))","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260317:nFWN404121:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1515","BK1161","BK1574","01672"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620428779","title":"Ascletis targets Q3 2026 FDA IND filing for ASC39 oral obesity tablets","url":"https://stock-news.laohu8.com/highlight/detail?id=2620428779","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620428779?lang=en_us&edition=fundamental","pubTime":"2026-03-17 18:01","pubTimestamp":1773741708,"startTime":"0","endTime":"0","summary":"Ascletis selected ASC39, an oral small-molecule amylin receptor agonist, as a clinical development candidate for obesity and said it expects to submit a U.S. FDA IND for ASC39 tablets in Q3 2026. Preclinical results were presented in the announcement, including a head-to-head cAMP assay in which ASC39 had an EC50 of 21.4 pM at hAMY1R and 846.1 pM at hCTR. In a diet-induced obese rat study, once-daily oral ASC39  produced 6.6% placebo-adjusted weight loss over 6 days. In the same study, eloralintide produced 5.6% placebo-adjusted weight loss with once-every-three-day subcutaneous dosing  over 6 days.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascletis Pharma Inc. published the original content used to generate this news brief via PR","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260317:nNDLXrsqL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672","BK1515","BK1574","BK1161"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1190050395","title":"ASCLETIS-B Selects Oral Amylin Receptor Agonist ASC39 as Clinical Candidate, Demonstrating Eloralintide-Like Selectivity and Efficacy in Preclinical Models","url":"https://stock-news.laohu8.com/highlight/detail?id=1190050395","media":"Stock News","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1190050395?lang=en_us&edition=fundamental","pubTime":"2026-03-17 17:52","pubTimestamp":1773741162,"startTime":"0","endTime":"0","summary":"ASCLETIS-B (01672) has announced its board of directors' decision to select ASC39, a potent and selective oral small molecule amylin receptor agonist, as a candidate for clinical development. 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