US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Crescent Biopharma Inc

16.60

-1.1500-6.48%

Post-market: 16.600.00000.00%16:10 EDT

Volume:163.00K

Turnover:2.72M

Market Cap:616.59M

PE:-2.24

High:17.65

Open:17.65

Low:16.14

Close:17.75

52wk High:27.41

52wk Low:8.72

Shares:37.14M

Float Shares:15.95M

Volume Ratio:1.01

T/O Rate:1.02%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-7.4105

EPS(LYR):-12.8150

ROE:-160.75%

ROA:-69.15%

PB:8.50

PE(LYR):-1.30

Loading ...

Overview Company News Filings

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K/A [Amend] - Current report

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Quarterly Report

10-Q - Quarterly report [Sections 13 or 15(d)]

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

[Rev.]Annual Report

10-K/A [Amend] - Annual report [Section 13 and 15(d), not S-K Item 405]

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Annual Report

10-K - Annual report [Section 13 and 15(d), not S-K Item 405]

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://au1.tigermoments.com/stock/CBIO/filings?page=5"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"CBIO","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","market":"US","secType":"STK","nameCN":"Crescent Biopharma Inc","latestPrice":16.6,"timestamp":1788206400000,"preClose":17.75,"halted":0,"volume":162999,"hourTrading":{"tag":"盘后","latestPrice":16.6,"preClose":16.6,"latestTime":"16:10 EDT","volume":2848,"amount":47276.8,"timestamp":1788207004864,"change":0,"changeRate":0,"amplitude":0},"delay":0,"changeRate":-0.06478873239436611,"floatShares":15953500,"shares":37143940,"eps":-7.4105,"marketStatus":"Closed","change":-1.15,"latestTime":"08-31 16:00:00 EDT","open":17.65,"high":17.65,"low":16.14,"amount":2715345,"amplitude":0.08507,"askPrice":0,"askSize":0,"bidPrice":0,"bidSize":0,"shortable":3,"etf":0,"ttmEps":-7.4105,"tradingStatus":0,"nextMarketStatus":{"tag":"Pre-Mkt","tradingStatus":1,"beginTime":1788249600000},"marketStatusCode":5,"adr":0,"adrRate":0,"listingDate":1389330000000,"exchange":"NASDAQ","adjPreClose":17.75,"postHourTrading":{"tag":"盘后","latestPrice":16.6,"preClose":16.6,"latestTime":"16:10 EDT","volume":2848,"amount":47276.8,"timestamp":1788207004864,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":1.012633,"impliedVol":0.2698,"impliedVolPercentile":0.2069},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","floatShares":15953500,"roa":"-69.15%","roe":"-160.75%","lyrEps":-12.814991,"volumeRatio":1.012633,"shares":37143940,"dividePrice":0,"high":17.65,"amplitude":0.08507,"preClose":17.75,"low":16.14,"week52Low":8.72,"pbRate":"8.50","psRate":"51.89","week52High":27.41,"institutionHeld":0.0724,"latestPrice":16.6,"eps":-7.4105,"divideRate":0,"volume":162999,"delay":0,"ttmEps":-7.4105,"open":17.65,"prevYearClose":11.86,"prevWeekClose":17.75,"prevMonthClose":14.47,"prevQuarterClose":18,"fiveDayClose":16.97,"twentyDayClose":14.87,"sixtyDayClose":18.45},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/CBIO\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-30","symbol":"CBIO","fiscalQuarterEnding":"2026/06","expectedEps":-0.78,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785384000000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2026-04-29","symbol":"CBIO","fiscalQuarterEnding":"2026/03","expectedEps":-0.85,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"post","actualEps":-0.7},{"market":"US","date":"2026-02-26","symbol":"CBIO","fiscalQuarterEnding":"2025/12","expectedEps":-2.22,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1772082000000,"reportTimeType":"pre","actualEps":-4.01},{"market":"US","date":"2025-11-06","symbol":"CBIO","fiscalQuarterEnding":"2025/09","expectedEps":-1.01,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1762405200000,"reportTimeType":"pre","actualEps":-1.27},{"market":"US","date":"2025-07-31","symbol":"CBIO","fiscalQuarterEnding":"2025/06","expectedEps":-2.69,"name":null,"time":"","type":"earning","dateTimestamp":1753934400000,"reportTimeType":"","actualEps":-4.93}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"CBIO\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"CBIO\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.4444,"buy":0.4444,"hold":0.1111,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.4444,"analysts":9,"updateTime":1780545600000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/CBIO\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"CBIO","date":"2026-08-28","current":-2.240065,"percent":0.042683,"low":-7.394562,"twenty":-3.542402,"median":-0.979043,"eighty":-0.169318,"high":2.563796,"avg":-1.508709,"sd":2.12646,"marketCap":760146861},"quantilePoints":[{"date":"2021-09-03","current":-1.821747,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":140831997},{"date":"2021-09-10","current":-1.886665,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":145850509},{"date":"2021-09-17","current":-2.101704,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":162474331},{"date":"2021-09-24","current":-1.923181,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":148673422},{"date":"2021-10-01","current":-1.647282,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":127344746},{"date":"2021-10-08","current":-1.562077,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":120757948},{"date":"2021-10-15","current":-1.622937,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":125462804},{"date":"2021-10-22","current":-1.407898,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":108838982},{"date":"2021-10-29","current":-1.334866,"twenty":-4.254957,"median":-2.206531,"eighty":-1.217573,"marketCap":103193156},{"date":"2021-11-05","current":-1.253719,"twenty":-4.254957,"median":-2.206531,"eighty":-1.230021,"marketCap":96920016},{"date":"2021-11-12","current":-0.620853,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":53710598},{"date":"2021-11-19","current":-0.475624,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":41146716},{"date":"2021-11-26","current":-0.45384,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":39262133},{"date":"2021-12-03","current":-0.395748,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":34236580},{"date":"2021-12-10","current":-0.395748,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":34236580},{"date":"2021-12-17","current":-0.366703,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":31723804},{"date":"2021-12-23","current":-0.384856,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":33294289},{"date":"2021-12-31","current":-0.331848,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":28708472},{"date":"2022-01-07","current":-0.303637,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":26267937},{"date":"2022-01-14","current":-0.284866,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":24644056},{"date":"2022-01-21","current":-0.232366,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20102212},{"date":"2022-01-28","current":-0.200125,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17313030},{"date":"2022-02-04","current":-0.201832,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17460656},{"date":"2022-02-11","current":-0.189306,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":16377021},{"date":"2022-02-18","current":-0.215955,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18682493},{"date":"2022-02-25","current":-0.217371,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18804991},{"date":"2022-03-04","current":-0.241552,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20896878},{"date":"2022-03-11","current":-0.236287,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20441437},{"date":"2022-03-18","current":-0.243403,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21057067},{"date":"2022-03-25","current":-0.248813,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21525072},{"date":"2022-04-01","current":-0.236294,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20778002},{"date":"2022-04-08","current":-0.219111,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":19267104},{"date":"2022-04-14","current":-0.194197,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17076301},{"date":"2022-04-22","current":-0.20762,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18256690},{"date":"2022-04-29","current":-0.171466,"twenty":-4.23831,"median":-2.203543,"eighty":-1.225062,"marketCap":15077508},{"date":"2022-05-06","current":-0.175797,"twenty":-4.23831,"median":-2.203543,"eighty":-1.212181,"marketCap":15458380},{"date":"2022-05-13","current":-0.141671,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11338034},{"date":"2022-05-20","current":-0.149458,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11961280},{"date":"2022-05-27","current":-0.483772,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":38716775},{"date":"2022-06-03","current":-0.491638,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":39346316},{"date":"2022-06-10","current":-0.538836,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":43123562},{"date":"2022-06-17","current":-0.570301,"twenty":-4.23831,"median":-2.203543,"eighty":-1.204728,"marketCap":45641726},{"date":"2022-06-24","current":-0.593899,"twenty":-4.246633,"median":-2.205037,"eighty":-1.203969,"marketCap":47530350},{"date":"2022-07-01","current":-0.704026,"twenty":-4.246633,"median":-2.205037,"eighty":-1.190642,"marketCap":56343924},{"date":"2022-07-08","current":-0.711892,"twenty":-4.246633,"median":-2.205037,"eighty":-1.183449,"marketCap":56973465},{"date":"2022-07-15","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.17379,"marketCap":55084842},{"date":"2022-07-22","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.166615,"marketCap":55084842},{"date":"2022-07-29","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":55084842},{"date":"2022-08-05","current":-0.735491,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":58862089},{"date":"2022-08-12","current":-0.755157,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":60435941},{"date":"2022-08-19","current":-7.394562,"twenty":-4.319663,"median":-2.219417,"eighty":-1.173236,"marketCap":62639335},{"date":"2022-08-26","current":-6.948659,"twenty":-4.374472,"median":-2.231928,"eighty":-1.186522,"marketCap":58862089},{"date":"2022-09-02","current":-7.245928,"twenty":-4.467447,"median":-2.249855,"eighty":-1.198454,"marketCap":61380253},{"date":"2022-09-09","current":-7.245928,"twenty":-4.558156,"median":-2.284285,"eighty":-1.205949,"marketCap":61380253},{"date":"2022-09-16","current":-7.283086,"twenty":-4.607295,"median":-2.335818,"eighty":-1.223882,"marketCap":61695023},{"date":"2022-09-23","current":-1.818542,"twenty":-4.702259,"median":-2.339886,"eighty":-1.237407,"marketCap":15404869},{"date":"2022-09-30","current":-1.872794,"twenty":-4.702259,"median":-2.339886,"eighty":-1.24606,"marketCap":15864434},{"date":"2022-10-07","current":-1.9891,"twenty":-4.702259,"median":-2.339886,"eighty":-1.250381,"marketCap":16849666},{"date":"2022-10-14","current":-2.235462,"twenty":-4.702259,"median":-2.339886,"eighty":-1.264627,"marketCap":18936595},{"date":"2022-10-21","current":-2.143308,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":18155964},{"date":"2022-10-28","current":-2.158172,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":18281872},{"date":"2022-11-04","current":-2.07345,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17564195},{"date":"2022-11-11","current":-2.064904,"twenty":-4.702259,"median":-2.339886,"eighty":-1.341215,"marketCap":17491798},{"date":"2022-11-18","current":1.47314,"twenty":-4.702259,"median":-2.339886,"eighty":-1.340298,"marketCap":17505320},{"date":"2022-11-25","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17319529},{"date":"2022-12-02","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":17319529},{"date":"2022-12-09","current":1.350444,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":16047331},{"date":"2022-12-16","current":1.319704,"twenty":-4.702259,"median":-2.33949,"eighty":-1.264627,"marketCap":15682046},{"date":"2022-12-23","current":1.332954,"twenty":-4.702259,"median":-2.284285,"eighty":-1.246705,"marketCap":15839496},{"date":"2022-12-30","current":1.397879,"twenty":-4.702259,"median":-2.249855,"eighty":-1.238056,"marketCap":16611002},{"date":"2023-01-06","current":2.033511,"twenty":-4.702259,"median":-2.235462,"eighty":-1.228022,"marketCap":24164207},{"date":"2023-01-13","current":0.834057,"twenty":-4.702259,"median":-2.228683,"eighty":-1.205599,"marketCap":9911100},{"date":"2023-01-20","current":0.847084,"twenty":-4.603457,"median":-2.215921,"eighty":-1.195389,"marketCap":10065902},{"date":"2023-01-27","current":0.937321,"twenty":-4.472686,"median":-2.202049,"eighty":-1.178581,"marketCap":11138189},{"date":"2023-02-03","current":0.926201,"twenty":-4.288569,"median":-2.18711,"eighty":-1.155134,"marketCap":11006041},{"date":"2023-02-10","current":0.79434,"twenty":-4.214316,"median":-2.168359,"eighty":-1.126768,"marketCap":9439143},{"date":"2023-02-17","current":0.798471,"twenty":-4.189559,"median":-2.158428,"eighty":-0.733918,"marketCap":9488227},{"date":"2023-02-24","current":0.76352,"twenty":-4.166469,"median":-2.154549,"eighty":-0.722119,"marketCap":9072904},{"date":"2023-03-03","current":0.752081,"twenty":-4.104269,"median":-2.149915,"eighty":-0.702453,"marketCap":8936981},{"date":"2023-03-10","current":0.629435,"twenty":-4.033134,"median":-2.136015,"eighty":-0.69852,"marketCap":7479577},{"date":"2023-03-17","current":0.621492,"twenty":-4.001878,"median":-2.108214,"eighty":-0.69616,"marketCap":7385185},{"date":"2023-03-24","current":0.660891,"twenty":-3.965473,"median":-2.07345,"eighty":-0.690654,"marketCap":7853367},{"date":"2023-03-31","current":-0.948348,"twenty":-3.915415,"median":-2.065977,"eighty":-0.688294,"marketCap":7816283},{"date":"2023-04-06","current":-0.959343,"twenty":-3.889599,"median":-2.052815,"eighty":-0.688294,"marketCap":7906907},{"date":"2023-04-14","current":-1.006532,"twenty":-3.827716,"median":-2.025144,"eighty":-0.688294,"marketCap":8295833},{"date":"2023-04-21","current":-1.094952,"twenty":-3.800801,"median":-2.009658,"eighty":-0.688294,"marketCap":9024598},{"date":"2023-04-28","current":-1.035394,"twenty":-3.762866,"median":-1.990699,"eighty":-0.688294,"marketCap":8533720},{"date":"2023-05-05","current":-0.984999,"twenty":-3.721769,"median":-1.979984,"eighty":-0.688294,"marketCap":8118362},{"date":"2023-05-12","current":-1.034936,"twenty":-3.659217,"median":-1.959683,"eighty":-0.688294,"marketCap":8529944},{"date":"2023-05-19","current":1.307824,"twenty":-3.590813,"median":-1.953003,"eighty":-0.62356,"marketCap":8571480},{"date":"2023-05-26","current":1.269223,"twenty":-3.551824,"median":-1.941439,"eighty":-0.593899,"marketCap":8318489},{"date":"2023-06-02","current":1.225437,"twenty":-3.52457,"median":-1.933362,"eighty":-0.561113,"marketCap":8031514},{"date":"2023-06-09","current":1.293997,"twenty":-3.472925,"median":-1.931296,"eighty":-0.53097,"marketCap":8480856},{"date":"2023-06-16","current":1.429965,"twenty":-3.448626,"median":-1.923181,"eighty":-0.522991,"marketCap":9371988},{"date":"2023-06-23","current":1.832106,"twenty":-3.404905,"median":-1.909241,"eighty":-0.488682,"marketCap":12007624},{"date":"2023-06-30","current":1.947333,"twenty":-3.388492,"median":-1.894612,"eighty":-0.479372,"marketCap":12762820},{"date":"2023-07-07","current":1.958856,"twenty":-3.336284,"median":-1.890722,"eighty":-0.461086,"marketCap":12838340},{"date":"2023-07-14","current":2.017045,"twenty":-3.28054,"median":-1.87855,"eighty":-0.435864,"marketCap":13219714},{"date":"2023-07-21","current":2.369063,"twenty":-3.21113,"median":-1.860968,"eighty":-0.410271,"marketCap":15526840},{"date":"2023-07-28","current":2.082724,"twenty":-3.161463,"median":-1.848291,"eighty":-0.373238,"marketCap":13650176},{"date":"2023-08-04","current":2.074083,"twenty":-3.143393,"median":-1.84,"eighty":-0.35976,"marketCap":13593537},{"date":"2023-08-11","current":1.957703,"twenty":-3.125944,"median":-1.827398,"eighty":-0.343256,"marketCap":12830788},{"date":"2023-08-18","current":-0.381172,"twenty":-3.078872,"median":-1.818996,"eighty":-0.332284,"marketCap":18124716},{"date":"2023-08-25","current":-0.415288,"twenty":-3.029373,"median":-1.817905,"eighty":-0.332284,"marketCap":19746943},{"date":"2023-09-01","current":-0.446994,"twenty":-2.989657,"median":-1.810594,"eighty":-0.332284,"marketCap":21254547},{"date":"2023-09-08","current":-0.420639,"twenty":-2.973696,"median":-1.810594,"eighty":-0.332284,"marketCap":20001375},{"date":"2023-09-15","current":-0.445556,"twenty":-2.960128,"median":-1.795851,"eighty":-0.332284,"marketCap":21186192},{"date":"2023-09-22","current":-0.394524,"twenty":-2.933767,"median":-1.789589,"eighty":-0.332284,"marketCap":18759596},{"date":"2023-09-29","current":-0.391329,"twenty":-2.919659,"median":-1.782149,"eighty":-0.332284,"marketCap":18607697},{"date":"2023-10-06","current":-0.343411,"twenty":-2.899577,"median":-1.776987,"eighty":-0.332284,"marketCap":16329203},{"date":"2023-10-13","current":-0.327439,"twenty":-2.883682,"median":-1.764944,"eighty":-0.328321,"marketCap":15569705},{"date":"2023-10-20","current":-0.320251,"twenty":-2.87071,"median":-1.755982,"eighty":-0.319653,"marketCap":15227931},{"date":"2023-10-27","current":-0.430462,"twenty":-2.848433,"median":-1.751781,"eighty":-0.315974,"marketCap":20468466},{"date":"2025-06-17","current":-0.345681,"twenty":-2.587053,"median":-1.08579,"eighty":-0.175718,"marketCap":10192829},{"date":"2025-07-25","current":-2.530939,"twenty":-2.520186,"median":-0.984999,"eighty":-0.169604,"marketCap":180881157},{"date":"2025-08-01","current":-2.414306,"twenty":-2.512378,"median":-0.984999,"eighty":-0.169604,"marketCap":172545620},{"date":"2025-08-08","current":-2.138274,"twenty":-2.502835,"median":-0.984999,"eighty":-0.169604,"marketCap":152818182},{"date":"2025-08-15","current":-2.707833,"twenty":-2.507436,"median":-0.984999,"eighty":-0.169604,"marketCap":193523388},{"date":"2025-08-22","current":-3.939042,"twenty":-2.518451,"median":-0.984999,"eighty":-0.169604,"marketCap":281515449},{"date":"2025-08-29","current":-3.870656,"twenty":-2.533218,"median":-0.984999,"eighty":-0.169604,"marketCap":276628028},{"date":"2025-09-05","current":-3.744825,"twenty":-2.546538,"median":-0.982021,"eighty":-0.169461,"marketCap":267635173},{"date":"2025-09-12","current":-3.432984,"twenty":-2.56751,"median":-0.984999,"eighty":-0.169604,"marketCap":245348534},{"date":"2025-09-19","current":-3.539667,"twenty":-2.58242,"median":-0.984999,"eighty":-0.169604,"marketCap":252972910},{"date":"2025-09-26","current":-3.394688,"twenty":-2.593613,"median":-0.984999,"eighty":-0.169604,"marketCap":242611578},{"date":"2025-10-03","current":-3.290741,"twenty":-2.627618,"median":-0.984999,"eighty":-0.169604,"marketCap":235182698},{"date":"2025-10-10","current":-3.356392,"twenty":-2.661594,"median":-0.984999,"eighty":-0.169604,"marketCap":239874622},{"date":"2025-10-17","current":-3.378276,"twenty":-2.67655,"median":-0.984999,"eighty":-0.169604,"marketCap":241438597},{"date":"2025-10-24","current":-3.498635,"twenty":-2.689355,"median":-0.984999,"eighty":-0.169604,"marketCap":250040458},{"date":"2025-10-31","current":-3.422043,"twenty":-2.698677,"median":-0.984999,"eighty":-0.169604,"marketCap":244566546},{"date":"2025-11-07","current":-3.583434,"twenty":-2.742274,"median":-0.984999,"eighty":-0.169604,"marketCap":256100860},{"date":"2025-11-14","current":-3.5506,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":253754301},{"date":"2025-11-21","current":-3.577955,"twenty":-2.801418,"median":-0.984999,"eighty":-0.169604,"marketCap":255709265},{"date":"2025-11-28","current":-4.116836,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":294222051},{"date":"2025-12-05","current":-3.553336,"twenty":-2.825536,"median":-0.984999,"eighty":-0.169604,"marketCap":253949797},{"date":"2025-12-12","current":-4.187958,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":299304957},{"date":"2025-12-19","current":-3.342707,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":238896576},{"date":"2025-12-26","current":-3.383738,"twenty":-2.870518,"median":-0.984999,"eighty":-0.169604,"marketCap":241829022},{"date":"2026-01-02","current":-3.244231,"twenty":-2.887152,"median":-0.984999,"eighty":-0.169604,"marketCap":231858706},{"date":"2026-01-09","current":-3.000777,"twenty":-2.947456,"median":-0.984999,"eighty":-0.169604,"marketCap":214459528},{"date":"2026-01-16","current":-3.419299,"twenty":-2.997495,"median":-0.984999,"eighty":-0.169604,"marketCap":244370475},{"date":"2026-01-23","current":-3.728404,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":266461565},{"date":"2026-01-30","current":-2.775103,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":198331077},{"date":"2026-02-06","current":-2.574048,"twenty":-2.983248,"median":-0.984999,"eighty":-0.169604,"marketCap":183962093},{"date":"2026-02-13","current":-2.524811,"twenty":-2.910905,"median":-0.984999,"eighty":-0.169604,"marketCap":180443158},{"date":"2026-02-20","current":-3.211406,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":229512750},{"date":"2026-02-27","current":-3.3769,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":241340281},{"date":"2026-03-06","current":-2.444514,"twenty":-2.837274,"median":-0.984999,"eighty":-0.169604,"marketCap":376313362},{"date":"2026-03-13","current":-2.494138,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":383952556},{"date":"2026-03-20","current":-2.291327,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":352731501},{"date":"2026-03-27","current":-2.912704,"twenty":-2.749773,"median":-0.984999,"eighty":-0.169604,"marketCap":448387501},{"date":"2026-04-02","current":-4.168403,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":641692335},{"date":"2026-04-10","current":-4.120937,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":634385279},{"date":"2026-04-17","current":-4.196452,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":646010141},{"date":"2026-04-24","current":-5.544926,"twenty":-2.829031,"median":-0.984999,"eighty":-0.169604,"marketCap":853596947},{"date":"2026-05-01","current":-4.828663,"twenty":-2.944974,"median":-0.984999,"eighty":-0.169604,"marketCap":743334005},{"date":"2026-05-08","current":-3.690363,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":598123026},{"date":"2026-05-15","current":-4.352579,"twenty":-3.088318,"median":-0.984999,"eighty":-0.169604,"marketCap":705452880},{"date":"2026-05-22","current":-4.147558,"twenty":-3.181319,"median":-0.984999,"eighty":-0.169604,"marketCap":672223823},{"date":"2026-05-29","current":-4.401783,"twenty":-3.236025,"median":-0.982021,"eighty":-0.169461,"marketCap":713427853},{"date":"2026-06-05","current":-3.782622,"twenty":-3.282788,"median":-0.984999,"eighty":-0.169604,"marketCap":613076101},{"date":"2026-06-12","current":-3.76007,"twenty":-3.344356,"median":-0.984999,"eighty":-0.169604,"marketCap":609420905},{"date":"2026-06-18","current":-3.733418,"twenty":-3.377721,"median":-0.984999,"eighty":-0.169604,"marketCap":605101127},{"date":"2026-06-26","current":-3.483293,"twenty":-3.392498,"median":-0.982021,"eighty":-0.169461,"marketCap":564561678},{"date":"2026-07-02","current":-3.501745,"twenty":-3.405077,"median":-0.982021,"eighty":-0.169461,"marketCap":567552293},{"date":"2026-07-10","current":-3.436138,"twenty":-3.419305,"median":-0.982021,"eighty":-0.169461,"marketCap":556918995},{"date":"2026-07-17","current":-3.097855,"twenty":-3.419307,"median":-0.982021,"eighty":-0.169461,"marketCap":502091051},{"date":"2026-07-24","current":-4.342042,"twenty":-3.429702,"median":-0.982021,"eighty":-0.169461,"marketCap":703745165},{"date":"2026-07-31","current":-3.829564,"twenty":-3.446389,"median":-0.979043,"eighty":-0.169318,"marketCap":620684227},{"date":"2026-08-07","current":-4.258748,"twenty":-3.477142,"median":-0.979043,"eighty":-0.169318,"marketCap":703221448},{"date":"2026-08-14","current":-4.310589,"twenty":-3.491494,"median":-0.979043,"eighty":-0.169318,"marketCap":711781661},{"date":"2026-08-21","current":-4.206907,"twenty":-3.503795,"median":-0.979043,"eighty":-0.169318,"marketCap":694661236},{"date":"2026-08-28","current":-4.603491,"twenty":-3.542402,"median":-0.979043,"eighty":-0.169318,"marketCap":760146861}],"updateTime":1788233144849},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"CBIO\",pageSize:20,pageCount:5,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"15264782","market":"us","labels":[],"media":"sec.gov","original_id":"AN114036122027565-CBIO","pdf_url":"","pub_time":1659283200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/0001140361-22-027565-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EXHIBIT 99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_ex99-1.htm","primary":true,"translateUrl":"","linkName":"edge20002003x10_ex99-1.htm","type":"EX-99.1","id":"NTFILE9QYyzFHJ7VKN5pxB","market":"us","size":78101},{"description":"FORM 8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_8k.htm","primary":false,"translateUrl":"","linkName":"edge20002003x10_8k.htm","type":"8-K","id":"NTFILE8ztHRn2Fony21Ue3","market":"us","size":26556},{"description":"EXHIBIT 99.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122027565/edge20002003x10_ex99-2.htm","primary":false,"translateUrl":"","linkName":"edge20002003x10_ex99-2.htm","type":"EX-99.2","id":"NTFILE2Nxjvi55prKUr2Lc","market":"us","size":13627}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-08-01 00:00","pubTimestamp":1659283200,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15264780","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922084700-CBIO","pdf_url":"","pub_time":1659283200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/0001104659-22-084700-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/tm2222229d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm2222229d1_sc13da.htm","type":"SC 13D/A","id":"NTFILEGfJ7cLfGHVVyF6iU","market":"us","size":66600},{"description":"EXHIBIT 99.3","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922084700/tm2222229d1_ex99-3.htm","primary":false,"translateUrl":"","linkName":"tm2222229d1_ex99-3.htm","type":"EX-99.3","id":"NTFILE3YZX57BzzRiC4Axk","market":"us","size":7080}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-08-01 00:00","pubTimestamp":1659283200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15204914","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000426-CBIO","pdf_url":"","pub_time":1658419200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000426/0001171520-22-000426-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000426/eps10375_jds.htm","primary":true,"translateUrl":"","linkName":"eps10375_jds.htm","type":"SC 13D/A","id":"NTFILEDdiUzeuVCd9opaHb","market":"us","size":177289}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-07-22 00:00","pubTimestamp":1658419200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15175861","market":"us","labels":[],"media":"sec.gov","original_id":"AN114036122025671-CBIO","pdf_url":"","pub_time":1657468800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/0001140361-22-025671-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EXHIBIT 99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1.htm","primary":true,"translateUrl":"","linkName":"edge20002003x2_ex99-1.htm","type":"EX-99.1","id":"NTFILEBtRiLAepv9xZi9N8","market":"us","size":8409},{"description":"FORM 8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_8k.htm","primary":false,"translateUrl":"","linkName":"edge20002003x2_8k.htm","type":"8-K","id":"NTFILEFTeEVfLmS2be1BJq","market":"us","size":26765},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img01.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img01.jpg","type":"GRAPHIC","id":"NTFILE3Lejz5FhGRXKtG4d","market":"us","size":1987826},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img02.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img02.jpg","type":"GRAPHIC","id":"NTFILE9AvsAc4N3xJvv4Cx","market":"us","size":960631},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img03.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img03.jpg","type":"GRAPHIC","id":"NTFILE56vbinLhbeh82PZk","market":"us","size":988709},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img04.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img04.jpg","type":"GRAPHIC","id":"NTFILEHoEXPUrwsgnAd5rp","market":"us","size":1911312},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img05.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img05.jpg","type":"GRAPHIC","id":"NTFILEG9XNideCKyED3a3m","market":"us","size":890282},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img06.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img06.jpg","type":"GRAPHIC","id":"NTFILEC9SLVJ7eWjAKoXTM","market":"us","size":1238307},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img07.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img07.jpg","type":"GRAPHIC","id":"NTFILEARepPdmS33FGZw13","market":"us","size":1179160},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img08.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img08.jpg","type":"GRAPHIC","id":"NTFILEBLSv2Z2rXYV6RtaH","market":"us","size":1305162},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img09.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img09.jpg","type":"GRAPHIC","id":"NTFILE91iXjjC88gurYgC2","market":"us","size":1208575},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img10.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img10.jpg","type":"GRAPHIC","id":"NTFILE8WArovjoQHmmyWfo","market":"us","size":971264},{"description":"","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img11.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img11.jpg","type":"GRAPHIC","id":"NTFILEEFuUYfJomHPYXmsw","market":"us","size":1580465},{"description":"","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img12.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img12.jpg","type":"GRAPHIC","id":"NTFILE3eV4D1Yd2HdUq6GD","market":"us","size":1550840},{"description":"","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img13.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img13.jpg","type":"GRAPHIC","id":"NTFILE4PsAPpt7Hu58Xm3H","market":"us","size":430148},{"description":"","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000114036122025671/edge20002003x2_ex99-1img14.jpg","primary":false,"translateUrl":"","linkName":"edge20002003x2_ex99-1img14.jpg","type":"GRAPHIC","id":"NTFILE4Ch1seFw9QQCSX5r","market":"us","size":377198}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-07-11 00:00","pubTimestamp":1657468800,"title_zh":"8-K  - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15109024","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922076841-CBIO","pdf_url":"","pub_time":1656604800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/0001104659-22-076841-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/tm2220246d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm2220246d1_sc13da.htm","type":"SC 13D/A","id":"NTFILEGn7sMPTHPSmvXDkm","market":"us","size":71400},{"description":"EXHIBIT 99.2","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922076841/tm2220246d1_ex99-2.htm","primary":false,"translateUrl":"","linkName":"tm2220246d1_ex99-2.htm","type":"EX-99.2","id":"NTFILEAUkk676L98Rtsft6","market":"us","size":4985}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-07-01 00:00","pubTimestamp":1656604800,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15109027","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522181696-CBIO","pdf_url":"","pub_time":1656259200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/0001193125-22-181696-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/d387575dex991.htm","primary":true,"translateUrl":"","linkName":"d387575dex991.htm","type":"EX-99.1","id":"NTFILEEoaDvjz2kNTW7sV5","market":"us","size":210398},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522181696/d387575d8k.htm","primary":false,"translateUrl":"","linkName":"d387575d8k.htm","type":"8-K","id":"NTFILE9eAhefUeNJ9GgZ51","market":"us","size":33225}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-06-27 00:00","pubTimestamp":1656259200,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15072804","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922073028-CBIO","pdf_url":"","pub_time":1655740800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/0001104659-22-073028-index.htm","us_notice_code":"Form SC 13D","us_title_en":"SC 13D  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/tm2218945d1_sc13d.htm","primary":true,"translateUrl":"","linkName":"tm2218945d1_sc13d.htm","type":"SC 13D","id":"NTFILE9QtQLDA8c8JJZS7R","market":"us","size":99245},{"description":"EXHIBIT 99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922073028/tm2218945d1_ex99-1.htm","primary":false,"translateUrl":"","linkName":"tm2218945d1_ex99-1.htm","type":"EX-99.1","id":"NTFILEHSEmyyEJ5osFTcjD","market":"us","size":6752}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-06-21 00:00","pubTimestamp":1655740800,"title_zh":"SC 13D  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15038878","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000371-CBIO","pdf_url":"","pub_time":1655395200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000371/0001171520-22-000371-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000371/eps10316.htm","primary":true,"translateUrl":"","linkName":"eps10316.htm","type":"SC 13D/A","id":"NTFILE8b7cf7ZmrcJ8PsEw","market":"us","size":148494}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-06-17 00:00","pubTimestamp":1655395200,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"15005141","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522170374-CBIO","pdf_url":"","pub_time":1654704000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522170374/0001193125-22-170374-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522170374/d366052d8k.htm","primary":true,"translateUrl":"","linkName":"d366052d8k.htm","type":"8-K","id":"NTFILEBu67fRigzCvhY7H4","market":"us","size":26169}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-06-09 00:00","pubTimestamp":1654704000,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14935803","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000347-CBIO","pdf_url":"","pub_time":1653408000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000347/0001171520-22-000347-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000347/eps10285.htm","primary":true,"translateUrl":"","linkName":"eps10285.htm","type":"SC 13D/A","id":"NTFILE2ZtXpXSjsau6Z6Kr","market":"us","size":182900}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-25 00:00","pubTimestamp":1653408000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14935804","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522157739-CBIO","pdf_url":"","pub_time":1653321600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K/A [Amend]  - Current report","symbol":"CBIO","title":"8-K/A [Amend]  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/0001193125-22-157739-index.htm","us_notice_code":"Form 8-K/A","us_title_en":"8-K/A [Amend]  - Current report","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/d354796d8ka.htm","primary":true,"translateUrl":"","linkName":"d354796d8ka.htm","type":"8-K/A","id":"NTFILECiG7yiegM3ZwTMnM","market":"us","size":26634},{"description":"EX-99.2","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522157739/d354796dex992.htm","primary":false,"translateUrl":"","linkName":"d354796dex992.htm","type":"EX-99.2","id":"NTFILEpTNHfuDCVE1wpknR","market":"us","size":78745}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-24 00:00","pubTimestamp":1653321600,"title_zh":"8-K/A [Amend]  - Current report","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14909028","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522156879-CBIO","pdf_url":"","pub_time":1653235200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/0001193125-22-156879-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 2.01: Completion of Acquisition or Disposition of Assets;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/d304590dex991.htm","primary":true,"translateUrl":"","linkName":"d304590dex991.htm","type":"EX-99.1","id":"NTFILEAMCvsaXSyvApYqkz","market":"us","size":95571},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/d304590d8k.htm","primary":false,"translateUrl":"","linkName":"d304590d8k.htm","type":"8-K","id":"NTFILEE6JxocTt54EM3eWt","market":"us","size":26814},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522156879/g304590dsp05.jpg","primary":false,"translateUrl":"","linkName":"g304590dsp05.jpg","type":"GRAPHIC","id":"NTFILE4eszhZe3TPuZ6rR9","market":"us","size":3929}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-23 00:00","pubTimestamp":1653235200,"title_zh":"8-K  - Current report","summary_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 2.01: Completion of Acquisition or Disposition of Assets;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14854499","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000299-CBIO","pdf_url":"","pub_time":1652112000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000299/0001171520-22-000299-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000299/eps10231.htm","primary":true,"translateUrl":"","linkName":"eps10231.htm","type":"SC 13D/A","id":"NTFILE9vnWaaKKDeNRUfF5","market":"us","size":148312}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-10 00:00","pubTimestamp":1652112000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14854501","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522144986-CBIO","pdf_url":"","pub_time":1652025600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/0001193125-22-144986-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/d300508dex991.htm","primary":true,"translateUrl":"","linkName":"d300508dex991.htm","type":"EX-99.1","id":"NTFILE9KWGwytkbrEM3GK5","market":"us","size":54328},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/d300508d8k.htm","primary":false,"translateUrl":"","linkName":"d300508d8k.htm","type":"8-K","id":"NTFILE4aWBqpaYnNMAbXRt","market":"us","size":25899},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522144986/g300508g95s42.jpg","primary":false,"translateUrl":"","linkName":"g300508g95s42.jpg","type":"GRAPHIC","id":"NTFILE41LU6pTGnCF1tk3C","market":"us","size":9098}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-05-09 00:00","pubTimestamp":1652025600,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14824735","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459022018775-CBIO","pdf_url":"","pub_time":1652025600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-Q  - Quarterly report [Sections 13 or 15(d)]","symbol":"CBIO","title":"10-Q  - Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/0001564590-22-018775-index.htm","us_notice_code":"Form 10-Q","us_title_en":"10-Q  - Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-10q_20220331.htm","primary":true,"translateUrl":"","linkName":"cbio-10q_20220331.htm","type":"10-Q","id":"NTFILECT6GfQ9sy53CLuvX","market":"us","size":1297805},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex311_6.htm","primary":false,"translateUrl":"","linkName":"cbio-ex311_6.htm","type":"EX-31.1","id":"NTFILE9CwiNVGoNGpcW2Lb","market":"us","size":14280},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex312_9.htm","primary":false,"translateUrl":"","linkName":"cbio-ex312_9.htm","type":"EX-31.2","id":"NTFILE9YznEQxyLgu4KmDY","market":"us","size":14287},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex321_7.htm","primary":false,"translateUrl":"","linkName":"cbio-ex321_7.htm","type":"EX-32.1","id":"NTFILE5cV6pczoaTkEuvx2","market":"us","size":9778},{"description":"EX-32.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/cbio-ex322_8.htm","primary":false,"translateUrl":"","linkName":"cbio-ex322_8.htm","type":"EX-32.2","id":"NTFILEDeiRAGzaBeuxMJXJ","market":"us","size":9784},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022018775/gzuqpypd2gjn000001.jpg","primary":false,"translateUrl":"","linkName":"gzuqpypd2gjn000001.jpg","type":"GRAPHIC","id":"NTFILEDEM431PPcUv7nk6y","market":"us","size":498835}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2022-05-09 00:00","pubTimestamp":1652025600,"title_zh":"10-Q  - Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14784999","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000271-CBIO","pdf_url":"","pub_time":1651420800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000271/0001171520-22-000271-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000271/eps10200.htm","primary":true,"translateUrl":"","linkName":"eps10200.htm","type":"SC 13D/A","id":"NTFILEE6YuhTwTu6VAWg1D","market":"us","size":145613}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-05-02 00:00","pubTimestamp":1651420800,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14784506","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522136435-CBIO","pdf_url":"","pub_time":1651420800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"CBIO","title":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"[Rev.]Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/0001193125-22-136435-index.htm","us_notice_code":"Form 10-K/A","us_title_en":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 10-K/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187d10ka.htm","primary":true,"translateUrl":"","linkName":"d212187d10ka.htm","type":"10-K/A","id":"NTFILECJZi3SPxMdNGMB73","market":"us","size":424161},{"description":"EX-31.03","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187dex3103.htm","primary":false,"translateUrl":"","linkName":"d212187dex3103.htm","type":"EX-31.03","id":"NTFILE7KHjnqfckpXkoYP7","market":"us","size":3230},{"description":"EX-31.04","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522136435/d212187dex3104.htm","primary":false,"translateUrl":"","linkName":"d212187dex3104.htm","type":"EX-31.04","id":"NTFILECGUmeZ9nEu98P93c","market":"us","size":3242}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"[Rev.]Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"[Rev.]Annual Report","pubTime":"2022-05-02 00:00","pubTimestamp":1651420800,"title_zh":"10-K/A [Amend]  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14645699","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000251-CBIO","pdf_url":"","pub_time":1650470400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000251/0001171520-22-000251-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000251/eps10184.htm","primary":true,"translateUrl":"","linkName":"eps10184.htm","type":"SC 13D/A","id":"NTFILE2PQx4Y4Pejvaruvf","market":"us","size":141739}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-04-21 00:00","pubTimestamp":1650470400,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14556807","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522095321-CBIO","pdf_url":"","pub_time":1649088000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/0001193125-22-095321-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-10.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex101.htm","primary":true,"translateUrl":"","linkName":"d313223dex101.htm","type":"EX-10.1","id":"NTFILEDEHW7S3yq1sm4M8w","market":"us","size":27543},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223d8k.htm","primary":false,"translateUrl":"","linkName":"d313223d8k.htm","type":"8-K","id":"NTFILEGgPYXqLTLDQUvo1q","market":"us","size":33341},{"description":"EX-10.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex102.htm","primary":false,"translateUrl":"","linkName":"d313223dex102.htm","type":"EX-10.2","id":"NTFILEGhxasT7NqpGTmxCA","market":"us","size":11275},{"description":"EX-99.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex991.htm","primary":false,"translateUrl":"","linkName":"d313223dex991.htm","type":"EX-99.1","id":"NTFILE5jeAc1mk78EM3eSv","market":"us","size":58092},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223dsp001.jpg","primary":false,"translateUrl":"","linkName":"g313223dsp001.jpg","type":"GRAPHIC","id":"NTFILEHzb914A84rrShdfJ","market":"us","size":4231},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223g0405021300120.jpg","primary":false,"translateUrl":"","linkName":"g313223g0405021300120.jpg","type":"GRAPHIC","id":"NTFILE3XVgBQWTJVqaYiZ8","market":"us","size":8804}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-04-05 00:00","pubTimestamp":1649088000,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14517465","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459022012877-CBIO","pdf_url":"","pub_time":1648656000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"CBIO","title":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/0001564590-22-012877-index.htm","us_notice_code":"Form 10-K","us_title_en":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-10k_20211231.htm","primary":true,"translateUrl":"","linkName":"cbio-10k_20211231.htm","type":"10-K","id":"NTFILECB4L9n75hhRE9SHi","market":"us","size":2732531},{"description":"EX-10.8","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex108_9.htm","primary":false,"translateUrl":"","linkName":"cbio-ex108_9.htm","type":"EX-10.8","id":"NTFILEGBb7ypNE2vXMitsD","market":"us","size":72186},{"description":"EX-23.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex231_8.htm","primary":false,"translateUrl":"","linkName":"cbio-ex231_8.htm","type":"EX-23.1","id":"NTFILE64EGve9vsXgGYw94","market":"us","size":3867},{"description":"EX-31.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex311_11.htm","primary":false,"translateUrl":"","linkName":"cbio-ex311_11.htm","type":"EX-31.1","id":"NTFILE5tbvhjHHmd1tfT4d","market":"us","size":17802},{"description":"EX-31.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex312_6.htm","primary":false,"translateUrl":"","linkName":"cbio-ex312_6.htm","type":"EX-31.2","id":"NTFILEGGerxbBw59ZedhKj","market":"us","size":17690},{"description":"EX-32.1","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex321_7.htm","primary":false,"translateUrl":"","linkName":"cbio-ex321_7.htm","type":"EX-32.1","id":"NTFILECzAUNPeK2udRCcoE","market":"us","size":5338},{"description":"EX-32.2","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex322_10.htm","primary":false,"translateUrl":"","linkName":"cbio-ex322_10.htm","type":"EX-32.2","id":"NTFILECS4MtedtEZzqMiPM","market":"us","size":5279},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000001.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000001.jpg","type":"GRAPHIC","id":"NTFILEG4o1SaG7iSudFgmS","market":"us","size":130550},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000002.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000002.jpg","type":"GRAPHIC","id":"NTFILE28AP3hsTgeYu2613","market":"us","size":238619},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000003.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000003.jpg","type":"GRAPHIC","id":"NTFILEGewBFtrnzqGYaDcC","market":"us","size":130550}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Annual Report","pubTime":"2022-03-31 00:00","pubTimestamp":1648656000,"title_zh":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":14,"pageCount":5,"totalSize":268,"code":"91000000","status":"200"}]}}