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Mereo Biopharma Group Plc

0.2668

+0.01435.66%

Post-market: 0.2616-0.0052-1.95%19:15 EDT

Volume:1.31M

Turnover:359.05K

Market Cap:42.46M

PE:-1.52

High:0.2880

Open:0.2525

Low:0.2525

Close:0.2525

52wk High:2.37

52wk Low:0.2000

Shares:159.13M

Float Shares:131.00M

Volume Ratio:1.11

T/O Rate:1.00%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.1753

EPS(LYR):-0.2627

ROE:-67.85%

ROA:-42.46%

PB:1.48

PE(LYR):-1.02

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Overview Company News Filings

Mereo BioPharma Group Q4 EPS $(0.01), Inline

Benzinga Earnings

UK's Mereo BioPharma misses 2025 revenue estimates, expects cash runway to mid-2027

Mereo BioPharma FY Revenue USD 500 Thousand Vs. IBES Estimate USD 520 Thousand

Mereo BioPharma FY 2025 cash and cash equivalents fall 41.28% to USD 40.99 million

Press Release: Mereo BioPharma Reports Full Year 2025 Financial Results and Provides Corporate Highlights

European Equities Traded in US as ADRs Fall in Wednesday Trading

MT Newswires Live

Mereo BioPharma faces securities class action over setrusumab bone mineral density claims

European Equities Traded in the US as American Depositary Receipts Decline in Friday Trading

MT Newswires Live

Class Action Lawsuit Targets Mereo BioPharma Over Allegedly Misleading Trial Claims

Mereo BioPharma CEO and CSO named as defendants in securities class action

European Equities Traded in the US as American Depositary Receipts Decline in Monday Trading

MT Newswires Live

Rosen Law Firm Urges Mereo BioPharma ADS Investors to Act by April 6 Lead Plaintiff Deadline

Robbins LLP Files Class Action Against Mereo BioPharma Group plc

Mereo BioPharma Faces Securities Fraud Class Action Lawsuit

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IBES Estimate USD 520 Thousand","url":"https://stock-news.laohu8.com/highlight/detail?id=2620228458","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620228458?lang=en_us&edition=fundamental","pubTime":"2026-03-19 20:43","pubTimestamp":1773924195,"startTime":"0","endTime":"0","summary":"Mar 19 (Reuters) - Mereo BioPharma FY operating income USD -40.107 million.:  ((Reuters Investor Briefs; email: reutersinvestor.briefs@thomsonreuters.com))  Source Date/Time = 19-MAR-202612:14:55.787 GMT","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260319:nRSD6FsdLf:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","BK4139","MREO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620283852","title":"Mereo BioPharma FY 2025 cash and cash equivalents fall 41.28% to USD 40.99 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2620283852","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620283852?lang=en_us&edition=fundamental","pubTime":"2026-03-19 20:31","pubTimestamp":1773923493,"startTime":"0","endTime":"0","summary":"Mereo published a full-year earnings release, reporting revenue of USD 0.5 million and net loss of USD 41.88 million.R&D expense fell 14.95% to USD 17.77 million, driven by lower alvelestat and etigilimab spending after completion of Phase 3 preparation activities in 2024, partly offset by higher setrusumab costs under a manufacturing and supply agreement with Ultragenyx.G&A expense decreased 12.96% to USD 23.01 million, mainly due to a lower annual cash bonus accrual and reduced professional fees.Cash and cash equivalents declined 41.28% to USD 40.99 million, which Mereo said is expected to fund operating expenses and capital expenditure requirements into mid-2027.Business updates included ongoing additional analyses from the Phase 3 Orbit and Cosmic setrusumab studies after missing primary fracture-rate endpoints, completion of site feasibility work for a global Phase 3 alvelestat trial, and āshibio’s plan to initiate a Phase 2 study of vantictumab in osteopetrosis in the second half","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260319:nNDL3QjtZl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BN0W2T93.GBP","BK4112","IE00BGHQF748.EUR","IE00B64PRP62.GBP","BK4585","IE00BN0W2V16.EUR","IE00BN0W2W23.USD","LU0314104364.USD","SG9999014039.USD","MREO","SG9999014021.USD","BK4588","IE00B3QW5Z07.USD","NDAQ","LU2210150020.SGD","LU2210149790.SGD","BK4139","IE00BKPKM429.USD","BK4505","LU2095319765.USD","SG9999014005.SGD","SG9999014013.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620283322","title":"Press Release: Mereo BioPharma Reports Full Year 2025 Financial Results and Provides Corporate Highlights","url":"https://stock-news.laohu8.com/highlight/detail?id=2620283322","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620283322?lang=en_us&edition=fundamental","pubTime":"2026-03-19 20:30","pubTimestamp":1773923400,"startTime":"0","endTime":"0","summary":"Additional data analyses from Orbit and Cosmic Phase 3 studies of setrusumab  in osteogenesis imperfecta ongoing. Cash of $41.0 million as of December 31, 2025, expected to provide runway into mid-2027. LONDON, March 19, 2026  -- Mereo BioPharma Group plc  , a clinical-stage biopharmaceutical company focused on rare diseases, today announced financial results for the full year ended December 31, 2025, and provided an update on recent corporate developments.-- As announced on December 29, 2025, the Phase 3 Orbit and Cosmic studies. of setrusumab in OI did not achieve statistical significance against the. primary endpoints of reduction in annualized clinical fracture rate. -- Both studies achieved high statistical significance against the key. secondary endpoint of improvement in bone mineral density versus a. -- The improvement in bone mineral density in the Cosmic study was. associated with a decreased rate of fracture in this younger, more. highly fracturing patient population, althou","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","OI","MREO","BK4126","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620574972","title":"European Equities Traded in US as ADRs Fall in Wednesday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2620574972","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620574972?lang=en_us&edition=fundamental","pubTime":"2026-03-18 23:04","pubTimestamp":1773846263,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts fell late Wednesday morning with the S&P Europe Select ADR Index dropping 0.9% to 1,734.7.From continental Europe, the gainers were led by biopharmaceutical company Cellectis  and petroleum refiner Equinor , which rose 4% and 1.5%, respectively. They were followed by lenders Banco Bilbao Vizcaya Argentaria  and ING , which were up 0.3% and 0.2%, respectively.The decliners from continental Europe were led by furniture maker Natuzzi  and biotech firm BioNTech , which fell 10% and 3.4%, respectively. They were followed by pharmaceutical company Novo Nordisk  and consumer goods company Unilever , which were down 3.2% and 3%, respectively.The gainers from the UK were led by biotech firm Trinity Biotech  and oil and gas company BP , which advanced 3.6% and 1.7%, respectively. They were followed by lender Barclays  and pharmaceutical company Silence Therapeutics , which increased 0.9% and 0.3%, respectively.The decliners from ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4532","BK4207","NVO.AU","BP","AUTL","BK4551","BK7104","BK4201","UN","AKTX","BK4588","MREO","BK4521","NVOX","BNTX","SLN","BK4183","ULVR.UK","LU0162691827.USD","UL","NTZ","CLLS","LU0154236417.USD","BK4568","BPH","LU0689626769.HKD","LU0124676726.USD","BK4095","BK4599","EQNR","LU0072461881.USD","LU1829250122.USD","BK4007","IE00BKVL7J92.USD","NVOH","BBVA","BK4505","BK4139","IE00BZ1G4Q59.USD","LU1093756168.USD","BK4548","ING.AU","TRIB","BK7141","BCS","ING","NVO","BK4082","BK4585","BCYC"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2620259899","title":"Mereo BioPharma faces securities class action over setrusumab bone mineral density claims","url":"https://stock-news.laohu8.com/highlight/detail?id=2620259899","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620259899?lang=en_us&edition=fundamental","pubTime":"2026-03-18 21:06","pubTimestamp":1773839161,"startTime":"0","endTime":"0","summary":"A securities class action is pending against Mereo, with an alleged class period from June 5, 2023 through December 26, 2025. The complaint alleges the company made repeated statements that setrusumab-driven bone mineral density gains would translate into reduced fracture rates in osteogenesis imperfecta patients. It also alleges Mereo cited Phase 2 results including a 67% reduction in annualized fracture rate, while omitting that the data lacked control-group comparisons needed to establish causation. The suit further alleges management knew the Phase 2 results could not distinguish setrusumab’s effects from changes due to standard of care or placebo effects. A court deadline to apply for lead plaintiff appointment has been set for April 6, 2026.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260318:nNDL4nGnZy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MREO","BK4505","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2619711926","title":"European Equities Traded in the US as American Depositary Receipts Decline in Friday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2619711926","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2619711926?lang=en_us&edition=fundamental","pubTime":"2026-03-14 00:11","pubTimestamp":1773418305,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were lower late Friday morning, declining 0.29% to 1,721.83 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by biotech firm Evaxion  and biopharmaceutical company Cellectis , which rose 8.3% and 7.8% respectively. They were followed by telecommunications Nokia  and medical device maker EDAP , which increased 3.6% and 2.9% respectively.The decliners from continental Europe were led by 3D printer company Materialise  and accommodations booking site trivago , which fell 2.2% and 2% respectively. They were followed by lender ING   biopharmaceutical company Grifols , which were down 1.8% and 1.7% respectively.The gainers from the UK and Ireland were led by biopharmaceutical company Mereo BioPharma Group  and cruise line operator Carnival , which advanced 3.2% and 1.1% respectively. They were followed by telecommunications operator Vodafone  and alcoholic beverage company Diageo , which were u","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AKTX","BHP","BK4117","BK4020","BK4505","BK7505","BK4169","BK7141","CLLS","BK4007","BK4559","BK4585","EDAP","MREO","NOK","BK4588","IE00BMPRXR70.SGD","BK4168","DGE.UK","DEO","BDRX","CUK","GRFS","LNOK","BK4142","BK4023","BK4132","EVAX","BK4107","LU0300736062.USD","BCYC","BK7507","BK4207","BK4077","BK4139","TRVG","ING.AU","BK4532","ING","BK4547","VOD","IE00BMPRXN33.USD","BHP.AU","BK7095","BK4546","BK7511","AFG","MTLS","BK4082","LU0300736492.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2619119192","title":"Class Action Lawsuit Targets Mereo BioPharma Over Allegedly Misleading Trial Claims","url":"https://stock-news.laohu8.com/highlight/detail?id=2619119192","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2619119192?lang=en_us&edition=fundamental","pubTime":"2026-03-14 00:00","pubTimestamp":1773417636,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against Mereo BioPharma and certain officers, seeking damages for alleged violations of U.S. federal securities laws. The suit covers investors who purchased or acquired Mereo securities between June 5, 2023 and December 26, 2025. The complaint alleges the company made false or misleading statements and concealed adverse facts about the Phase 3 ORBIT and COSMIC programs. It also alleges the trials did not meet their primary endpoints for reducing annualized clinical fracture rates versus placebo or bisphosphonate control groups. A case page is available at bgandg.com/MREO.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260313:nNDLbMwTtY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014021.USD","SG9999014013.SGD","NDAQ","LU0314104364.USD","IE00B64PRP62.GBP","IE00B3QW5Z07.USD","LU2210149790.SGD","BK4505","IE00BGHQF748.EUR","SG9999014039.USD","LU2095319765.USD","LU2210150020.SGD","BK4112","SG9999014005.SGD","BK4585","BK4588","MREO","BK4139","IE00BKPKM429.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618940311","title":"Mereo BioPharma CEO and CSO named as defendants in securities class action","url":"https://stock-news.laohu8.com/highlight/detail?id=2618940311","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618940311?lang=en_us&edition=fundamental","pubTime":"2026-03-11 21:02","pubTimestamp":1773234147,"startTime":"0","endTime":"0","summary":"Mereo BioPharma is facing a securities class action that names CEO Denise Scots-Knight and CSO John Lewicki as individual defendants under Section 20 control-person claims. The complaint alleges the executives had authority over the company’s public statements and participated in investor communications that contained materially misleading statements about the setrusumab program. It also alleges they had access to non-public information that contradicted their public statements. Investors seeking to be considered for lead plaintiff must file by April 6, 2026.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260311:nNDL58G1hW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MREO","BK4505","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618209486","title":"European Equities Traded in the US as American Depositary Receipts Decline in Monday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2618209486","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618209486?lang=en_us&edition=fundamental","pubTime":"2026-03-09 23:30","pubTimestamp":1773070209,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were tracking slightly lower late Monday morning, declining 0.30% to 1,727.53 on the S&P Europe Select ADR Index.From continental Eur","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["TRIB","BK4588","IE00BZ1G4Q59.USD","BK4201","NCNA","LU0154236417.USD","LU1093756168.USD","BK7104","NVOH","BK4532","EVAX","BK4082","LU1093756325.SGD","IE00BFMHRM44.USD","BK4505","NVO.AU","NVOX","BK4142","BK7119","MREO","CRTO","SLN","BK4599","BUD.AU","BK4117","CUK","AFG","BK4139","BUD","DBVT","BK4009","IE00BKVL7J92.USD","TRVG","BK4158","BK4107","E","AUTL","EQNR","NVO","BDRX","BK4077","BCYC","BK4007","BK4585"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2617599363","title":"Rosen Law Firm Urges Mereo BioPharma ADS Investors to Act by April 6 Lead Plaintiff Deadline","url":"https://stock-news.laohu8.com/highlight/detail?id=2617599363","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617599363?lang=en_us&edition=fundamental","pubTime":"2026-03-05 09:33","pubTimestamp":1772674393,"startTime":"0","endTime":"0","summary":"Rosen Law Firm is urging investors who bought Mereo BioPharma Group plc American Depositary Shares between June 5, 2023 and Dec. 26, 2025 to seek counsel ahead of an April 6, 2026 deadline to seek lead plaintiff status in a securities class action. The lawsuit alleges the company and others made misleading statements about expectations for Phase 3 ORBIT and COSMIC studies of setrusumab in osteogenesis imperfecta, and that both trials failed to meet their primary endpoints, allegedly inflating the share price and causing investor losses when the results became known.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260305:nNDL50TR6m:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","SG9999014039.USD","BK4139","IE00BGHQF748.EUR","LU2210149790.SGD","LU2095319765.USD","LU2210150020.SGD","IE00B64PRP62.GBP","LU0314104364.USD","NDAQ","SG9999014005.SGD","IE00B3QW5Z07.USD","SG9999014013.SGD","BK4585","SG9999014021.USD","MREO","IE00BKPKM429.USD","BK4588","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617851563","title":"Robbins LLP Files Class Action Against Mereo BioPharma Group plc","url":"https://stock-news.laohu8.com/highlight/detail?id=2617851563","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617851563?lang=en_us&edition=fundamental","pubTime":"2026-03-05 02:40","pubTimestamp":1772649650,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against Mereo BioPharma Group plc on behalf of investors who bought or acquired the company’s ADSs between June 5, 2023 and December 26, 2025. The suit alleges the company misled investors about the likelihood that its Phase 3 ORBIT and COSMIC studies of setrusumab in osteogenesis imperfecta would meet the primary endpoint of reducing annualized fracture rates; the company later reported the trials did not meet that endpoint, and the ADS price fell sharply. Investors seeking to be appointed lead plaintiff must file by April 6, 2026.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260304:nNDL8MZJRx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210150020.SGD","BK4588","BK4139","NDAQ","IE00B64PRP62.GBP","IE00B3QW5Z07.USD","IE00BGHQF748.EUR","SG9999014013.SGD","SG9999014005.SGD","BK4112","BK4585","LU0314104364.USD","LU2095319765.USD","MREO","BK4505","SG9999014039.USD","IE00BKPKM429.USD","SG9999014021.USD","LU2210149790.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616554557","title":"Mereo BioPharma Faces Securities Fraud Class Action Lawsuit","url":"https://stock-news.laohu8.com/highlight/detail?id=2616554557","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616554557?lang=en_us&edition=fundamental","pubTime":"2026-03-04 23:45","pubTimestamp":1772639118,"startTime":"0","endTime":"0","summary":"A federal securities fraud class action has been filed against Mereo BioPharma Group plc, with an April 6, 2026 deadline for investors to seek appointment as lead plaintiff. The suit alleges the company and certain executives made false or misleading statements or failed to disclose the true status of the Phase 3 ORBIT and COSMIC programs for setrusumab, which later were reported to have missed their primary endpoints. Mereo shares fell about 88% on December 29, 2025 after the trial results were announced.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260304:nNDL7vfn2N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3QW5Z07.USD","BK4112","SG9999014039.USD","BK4585","BK4139","IE00BGHQF748.EUR","IE00BKPKM429.USD","BK4505","LU2095319765.USD","BK4588","SG9999014013.SGD","SG9999014005.SGD","NDAQ","LU2210149790.SGD","MREO","LU2210150020.SGD","SG9999014021.USD","LU0314104364.USD","IE00B64PRP62.GBP"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":5,"pageCount":5,"totalSize":94,"code":"91000000","status":"200"}]}}