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Ultragenyx Pharmaceutical

26.53

+0.72002.79%

Post-market: 15.05-11.4800-43.27%19:59 EDT

Volume:7.17M

Turnover:139.69M

Market Cap:2.61B

PE:-4.55

High:26.80

Open:25.96

Low:25.57

Close:25.81

52wk High:39.89

52wk Low:18.29

Shares:98.32M

Float Shares:80.72M

Volume Ratio:4.36

T/O Rate:8.88%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-5.8279

EPS(LYR):-5.8316

ROE:-608.47%

ROA:-24.22%

PB:-8.96

PE(LYR):-4.55

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Overview Company News Filings

Ultragenyx's gene therapy helps control ammonia levels in late-stage study

Ultragenyx Phase 3 Enh3ance study showed statistically significant results

Ultragenyx reports Phase 3 Enh3ance trial shows DTX301 cuts plasma ammonia AUC by 18% at Week 36

Ultragenyx Announces Positive 36-Week Data From Phase 3 Study of Dtx301 Aav8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (Otc) Deficiency

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Dtx301 Shows 18% Reduction in 24-Hour Plasma Ammonia at Week 36 Versus Placebo

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Dtx301 Well Tolerated With Acceptable Safety Profile

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Fewer Hyperammonemic Crises and No Deaths in Dtx301 Group Compared to Placebo

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Secondary Endpoint Data on Treatment Burden Reduction Expected First Half 2027

THOMSON REUTERS

Ultragenyx Announces Positive 36-Week Data from Phase 3 Study of DTX301 AAV8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (OTC) Deficiency

Ultragenyx price target lowered to $74 from $120 at JPMorgan

Ultragenyx faces securities class action over August 2023–December 2025 disclosures

How Setrusumab Trial Setbacks and Securities Suits May Impact Ultragenyx Pharmaceutical (RARE) Investors

Simply Wall St.

Ultragenyx Faces Securities Class Action Over Setrusumab Trial Disclosures

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ammonia AUC by 18% at Week 36","url":"https://stock-news.laohu8.com/highlight/detail?id=2618134272","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618134272?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:33","pubTimestamp":1773318800,"startTime":"0","endTime":"0","summary":"Ultragenyx reported positive 36-week results from the Phase 3 Enh3ance trial of DTX301, an investigational AAV8 gene therapy for ornithine transcarbamylase deficiency. In the randomized, double-blind, placebo-controlled period, DTX301  reduced 24-hour plasma ammonia AUC0-24 by 18% versus placebo  at Week 36 . The company also reported a mean 27% reduction in ammonia scavenger medications at Week 36 among treated patients. The study is continuing to a second primary endpoint evaluating treatment burden through 64 weeks of follow-up, with data expected in the first half of 2027.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nNDL3swplM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4585","LU2210150020.SGD","LU0314104364.USD","BK4588","BK4139","IE00B64PRP62.GBP","SG9999014039.USD","IE00BKPKM429.USD","LU2210149790.SGD","SG9999014013.SGD","IE00BGHQF748.EUR","BK4112","SG9999014005.SGD","SG9999014021.USD","IE00B3QW5Z07.USD","NDAQ","LU2095319765.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618713448","title":"Ultragenyx Announces Positive 36-Week Data From Phase 3 Study of Dtx301 Aav8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (Otc) Deficiency","url":"https://stock-news.laohu8.com/highlight/detail?id=2618713448","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618713448?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618424134","title":"Ultragenyx Pharmaceutical Inc - 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Secondary Endpoint Data on Treatment Burden Reduction Expected First Half 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2618134425","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618134425?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618460132","title":"Ultragenyx Announces Positive 36-Week Data from Phase 3 Study of DTX301 AAV8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (OTC) Deficiency","url":"https://stock-news.laohu8.com/highlight/detail?id=2618460132","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618460132?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318600,"startTime":"0","endTime":"0","summary":"Statistically significant improvements in primary endpoint of ammonia control compared with placebo at 36 weeks Clinically important changes observed in patient global impression scale for overall OTC","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/03/12/3254660/20739/en/Ultragenyx-Announces-Positive-36-Week-Data-from-Phase-3-Study-of-DTX301-AAV8-Gene-Therapy-for-the-Treatment-of-Ornithine-Transcarbamylase-OTC-Deficiency.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618136393","title":"Ultragenyx price target lowered to $74 from $120 at JPMorgan","url":"https://stock-news.laohu8.com/highlight/detail?id=2618136393","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618136393?lang=en_us&edition=fundamental","pubTime":"2026-03-12 18:54","pubTimestamp":1773312883,"startTime":"0","endTime":"0","summary":"JPMorgan lowered the firm’s price target on Ultragenyx (RARE) to $74 from $120 and keeps an Overweight rating on the shares. At current share level...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-74-from-120-at-jpmorgan-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-74-from-120-at-jpmorgan-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU2023250843.SGD","LU0211327993.USD","LU0267386448.USD","LU0683600562.USD","LU0211326755.USD","LU0787776722.HKD","LU1496350171.SGD","LU0208291251.USD","IE00BJLML261.HKD","LU0964807845.USD","LU2237443895.HKD","LU0170899867.USD","LU0417517546.SGD","LU1064131342.USD","LU2746668974.SGD","LU2505996509.AUD","LU2023250504.SGD","LU0345769128.USD","LU1720051108.HKD","LU0238689110.USD","LU1244550494.USD","LU0971096721.USD","LU2756315664.SGD","BK4588","IE000M9KFDE8.USD","LU0211331839.USD","LU2357305700.SGD","LU0048584097.USD","LU0496365809.HKD","LU0211326839.USD","LU0820561818.USD","LU0345770993.USD","IE00B3S45H60.SGD","BK4516","LU1720051017.SGD","LU1145028129.USD","JPMO","LU2430703178.SGD","LU0868494708.USD","LU2264538146.SGD","LU2211815571.USD","LU0345770308.USD","LU0265550946.USD","IE00BKVL7J92.USD","LU1894683348.USD","RARE","IE00BJTD4N35.SGD","LU0820561909.HKD","IE00BYXW3230.USD","IE00BWXC8680.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618403199","title":"Ultragenyx faces securities class action over August 2023–December 2025 disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2618403199","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618403199?lang=en_us&edition=fundamental","pubTime":"2026-03-11 21:02","pubTimestamp":1773234138,"startTime":"0","endTime":"0","summary":"Ultragenyx is facing a pending securities class action covering the period from Aug. 3, 2023 to Dec. 26, 2025. Investors seeking to serve as lead plaintiff must file by April 6, 2026. The suit names Ultragenyx CEO Emil Kakkis and CMO Eric Crombez as individual defendants under Section 20 control-person claims. The complaint alleges they had authority over SEC filings and other public statements, and that they had access to non-public information related to study progress and risks.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260311:nNDL4bGSJ8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618959236","title":"How Setrusumab Trial Setbacks and Securities Suits May Impact Ultragenyx Pharmaceutical (RARE) Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2618959236","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618959236?lang=en_us&edition=fundamental","pubTime":"2026-03-10 21:21","pubTimestamp":1773148903,"startTime":"0","endTime":"0","summary":"In past months, several law firms announced securities class actions against Ultragenyx Pharmaceutical, alleging the company misled investors about the reliability and risks of Phase III Orbit and Cosmic trials for setrusumab in osteogenesis imperfecta, after the studies failed to reach statistical significance. \nThe litigation raises questions about Ultragenyx’s clinical disclosure practices and could influence how investors view the company’s risk profile, capital allocation, and future...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rare/ultragenyx-pharmaceutical/news/how-setrusumab-trial-setbacks-and-securities-suits-may-impac","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rare/ultragenyx-pharmaceutical/news/how-setrusumab-trial-setbacks-and-securities-suits-may-impac","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4528","BK4551","RARE","ISBC","AIYY","BK4211","AI","BK4139","BK4023","BK4585","BK4587","BK4588","BK4543"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617502663","title":"Ultragenyx Faces Securities Class Action Over Setrusumab Trial Disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2617502663","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617502663?lang=en_us&edition=fundamental","pubTime":"2026-03-08 03:05","pubTimestamp":1772910316,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical Inc. is facing a proposed securities class action in the U.S. District Court for the Northern District of California on behalf of investors who bought shares between Aug. 3, 2023 and Dec. 26, 2025. The suit alleges the company and certain executives made misleading statements and omissions about the prospects and interim benchmarks for setrusumab in Phase III Osteogenesis Imperfecta studies, before later disclosures that the Orbit and Cosmic trials failed to meet primary endpoints. Investors seeking to be appointed lead plaintiff have until April 6, 2026.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260307:nNDL4Vz2jS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","SG9999014039.USD","BK4585","LU2210149790.SGD","IE00B64PRP62.GBP","IE00BGHQF748.EUR","BK4139","NDAQ","LU2210150020.SGD","SG9999014005.SGD","IE00BKPKM429.USD","LU0314104364.USD","SG9999014021.USD","LU2095319765.USD","SG9999014013.SGD","BK4588","BK4112","IE00B3QW5Z07.USD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":8,"pageCount":8,"totalSize":153,"code":"91000000","status":"200"}]}}