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Septerna, Inc.

36.80

-0.7000-1.87%

Post-market: 36.800.00000.00%16:10 EDT

Volume:241.54K

Turnover:8.94M

Market Cap:1.72B

PE:-67.84

High:38.20

Open:37.72

Low:36.46

Close:37.50

52wk High:51.10

52wk Low:12.33

Shares:46.68M

Float Shares:22.90M

Volume Ratio:0.76

T/O Rate:1.05%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.5424

EPS(LYR):-1.1044

ROE:-6.34%

ROA:-7.13%

PB:4.44

PE(LYR):-33.32

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Overview Company News Filings

Earnings Flash (SEPN) Septerna Posts Q2 Loss Per Share $0.29, vs. FactSet Est of $0.43 Loss

MT Newswires Live

Septerna Q2 Revenue Beats Analyst Estimates, Driven by Novo Nordisk Partnership

Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate

Benzinga Earnings

Press Release: Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results

Septerna SVP Drug Discovery Daniel D. Long Sells USD 114,901.29 in Common Shares

3 Small-Cap Stocks Analysts Expect to Rally Big

3 Small-Cap Stocks with ‘Strong Buy’ Ratings and 40%+ Upside, According to Analysts

Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974

Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?

Simply Wall St.

Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20

Truist Securities Adjusts Septerna Price Target to $43 From $35, Maintains Buy Rating

MT Newswires Live

Septerna Price Target Maintained with a $40.00/share by HC Wainwright & Co.

Septerna is Maintained at Buy by Truist Securities

Septerna price target raised to $43 from $35 at Truist

Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN) and Strategy (MSTR)

Septerna price target lowered to $45 from $52 at Guggenheim

Septerna Buy Rating Reiterated as Analyst Sees Favorable Risk‑Reward and Keeps $40 Price Target Unchanged

Septerna Chief People Officer Samira Shaikhly Disposes of 2,178 Common Shares for $76,638.24

Septerna Holds Annual Shareholder Meeting

Cantor Fitzgerald Reaffirms Their Buy Rating on Septerna, Inc. (SEPN)

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Flash (SEPN) Septerna Posts Q2 Loss Per Share $0.29, vs. FactSet Est of $0.43 Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2658254959","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658254959?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:16","pubTimestamp":1786392982,"startTime":"0","endTime":"0","summary":"Earnings Flash (SEPN) Septerna Posts Q2 Loss Per Share $0.29, vs. FactSet Est of $0.43 Loss","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658295935","title":"Septerna Q2 Revenue Beats Analyst Estimates, Driven by Novo Nordisk Partnership","url":"https://stock-news.laohu8.com/highlight/detail?id=2658295935","media":"Reuters","labels":["corporation","dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658295935?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:08","pubTimestamp":1786392529,"startTime":"0","endTime":"0","summary":"Septerna Q2 revenue beats analyst estimates, driven by Novo Nordisk partnershipOverviewUS biotechnology firm's Q2 revenue rose and beat analyst expectationsNet loss for Q2 narrowed compared to prior y","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260810:nL1N4470V5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation,dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QTRX","BK4139","BK4121","SEPN","BK4505","LFSC","CANC","HRTX","BK4007","COGT"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658840959","title":"Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2658840959","media":"Benzinga Earnings","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658840959?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:06","pubTimestamp":1786392389,"startTime":"0","endTime":"0","summary":"Septerna (NASDAQ:SEPN) reported quarterly losses of $(0.29) per share which beat the analyst consensus estimate of $(0.43) by 32.56 percent. This is a 48.21 percent increase over losses of $(0.56) per share from the","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/08/61091200/septerna-q2-eps-0-29-beats-0-43-estimate-sales-26-746m-beat-17-875m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate","news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658411956","title":"Press Release: Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2658411956","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658411956?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:01","pubTimestamp":1786392060,"startTime":"0","endTime":"0","summary":"-- Septerna's Phase 1 clinical trial of SEP-479, a potent, selective. oral small molecule PTH1R agonist for the treatment of. serum calcium and endogenous serum PTH) in healthy volunteers.-- Based on pharmacokinetic data from the ongoing Phase 1 clinical. trial, the observed elimination half-life of SEP-479 is. approximately three to four days, which the Company anticipates. will support once-daily dosing. To fully characterize steady-state. pharmacokinetics, dosing for the MAD cohorts will be extended to. 14 days. As a result, Septerna expects to report Phase 1 data from. both the SAD and MAD cohorts in the first quarter of 2027.-- During the quarter, the Company presented the first detailed. preclinical characterization of SEP-479 in an oral presentation at. ENDO 2026, highlighting data supporting its potential as a. -- As reported in March 2026, SEP-631, an oral small molecule MRGPRX2","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN","R","PRGS","BK4097","BK4232","BK4022","GPCR","LU2065732104.USD","BK4599"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2657572937","title":"Septerna SVP Drug Discovery Daniel D. Long Sells USD 114,901.29 in Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2657572937","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2657572937?lang=en_us&edition=fundamental","pubTime":"2026-08-06 07:17","pubTimestamp":1785971827,"startTime":"0","endTime":"0","summary":"Septerna SVP Drug Discovery Daniel D. Long sells USD 114,901.29 in common sharesSepterna SVP, Drug Discovery Daniel D. Long sold 3,334 shares on Aug. 3 under a 10b5-1 plan.Sales priced at USD 33.98 an","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260805:nNDL7Mtvbt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Drug Discovery Daniel D. 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($SEPN), Kornit Digit...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-small-cap-stocks-analysts-expect-to-rally-big?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-small-cap-stocks-analysts-expect-to-rally-big?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2652211586","title":"3 Small-Cap Stocks with ‘Strong Buy’ Ratings and 40%+ Upside, According to Analysts","url":"https://stock-news.laohu8.com/highlight/detail?id=2652211586","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652211586?lang=en_us&edition=fundamental","pubTime":"2026-07-20 22:15","pubTimestamp":1784556959,"startTime":"0","endTime":"0","summary":"Small-cap stocks often go unnoticed, but a few are grabbing Wall Street’s attention. Analysts are highlighting Septerna, Inc. ($SEPN), Kornit Digit...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2652337002","title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","url":"https://stock-news.laohu8.com/highlight/detail?id=2652337002","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652337002?lang=en_us&edition=fundamental","pubTime":"2026-07-18 07:01","pubTimestamp":1784329288,"startTime":"0","endTime":"0","summary":"Septerna President and COO Elizabeth Bhatt sells 4,000 shares for $135,974Septerna President and COO Elizabeth Bhatt sold 4,000 shares on July 15 at USD 33.99.She exercised stock options for 4,000 sha","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260717:nNDL633WXk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650615176","title":"Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?","url":"https://stock-news.laohu8.com/highlight/detail?id=2650615176","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650615176?lang=en_us&edition=fundamental","pubTime":"2026-07-11 23:28","pubTimestamp":1783783710,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) recently joined several Russell growth and small cap indices. This change can affect how index-tracking and benchmark-aware funds treat the stock and influence overall investor attention.\nSee our latest analysis for Septerna.\nSepterna’s recent Russell index inclusions come after a strong run in the stock, with a 90 day share price return of 55.61% and a 1 year total shareholder return of 206.31%. This comes even though the latest close at $35.93 followed a 1 day share price...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648639940","title":"Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20","url":"https://stock-news.laohu8.com/highlight/detail?id=2648639940","media":"Reuters","labels":["insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648639940?lang=en_us&edition=fundamental","pubTime":"2026-07-03 07:00","pubTimestamp":1783033255,"startTime":"0","endTime":"0","summary":"Septerna SVP Drug Discovery Daniel D. Long disposes of 3,333 common shares worth $113,104.20Septerna SVP, Drug Discovery Daniel D. Long exercised stock options for 3,333 shares at USD 2.76 on July 1, ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260702:nNDL3WRqJz:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Drug Discovery Daniel D. 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