US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

SPYRE THERAPEUTICS INC

88.50

-0.8300-0.93%

Post-market: 88.500.00000.00%19:30 EDT

Volume:1.43M

Turnover:125.20M

Market Cap:7.80B

PE:-44.03

High:90.00

Open:87.06

Low:85.00

Close:89.33

52wk High:110.18

52wk Low:14.51

Shares:88.17M

Float Shares:80.98M

Volume Ratio:0.85

T/O Rate:1.76%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:8.17

PE(LYR):-44.80

Loading ...

Overview Company News Filings

Analysts Offer Insights on Healthcare Companies: Revolution Medicines (RVMD) and Spyre Therapeutics (SYRE)

U.S. Research Roundup-CrowdStrike, Nvidia, Macerich

Top Midday Decliners

MT Newswires Live

Spyre Therapeutics falls -13.2%

Spyre Therapeutics Down over 12%, on Pace for Largest Percent Decrease Since June 2024

U.S. Stocks on the MOVE-Semtech, Donaldson, Meta

Spyre Therapeutics (SYRE) Gets a Buy from LifeSci Capital

Analysts Offer Insights on Healthcare Companies: Solventum Corporation (SOLV), Argenx Se (ARGX) and Spyre Therapeutics (SYRE)

Spyre Therapeutics Reports Phase 2 Skyway RA Data for Spy072 Shows Statistically Significant Benefit vs Placebo

Spyre Therapeutics Shares Down 12.4% Premarket After Co's Experimental Drug Fails to Meet Threshold for Monotherapy Development in Rheumatoid Arthritis

THOMSON REUTERS

Spyre Therapeutics Inc : Btig Cuts Target Price to $121 from $132

THOMSON REUTERS

Stocks to Watch: Intuit, Spyre Therapeutics, Zoom Communications, nCino

Spyre Therapeutics Stock (SYRE) Tumbles 14% in After-Hours – Here’s What Spooked Investors

Spyre Therapeutics Won't Prioritize Rheumatoid Arthritis Monotherapy After Trial

Spyre Therapeutics announces results from RA sub-study of SKYWAY basket trial

Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-Study of the Skyway Phase 2 Trial of Spy072

THOMSON REUTERS

Spyre Therapeutics - Spy072 Well Tolerated with Adverse Event Rates Comparable to Placebo

THOMSON REUTERS

Spyre Therapeutics Inc: Spy072 in Combination with Il17-a/F in Hidradenitis Suppurativa (Hs) in Late 2027 or Early 2028

THOMSON REUTERS

Spyre Therapeutics - Topline Data for Spy072 in Psa and Axspa Expected Q4 2026

THOMSON REUTERS

Spyre Therapeutics Inc - Magnitude of Effect Did not Meet Company's Target to Prioritize Monotherapy Development of Spy072 in Rheumatoid Arthritis

THOMSON REUTERS

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://au1.tigermoments.com/stock/SYRE/news"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"SYRE","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SYRE\",,,,,undefined,":{"symbol":"SYRE","market":"US","secType":"STK","nameCN":"SPYRE THERAPEUTICS INC","latestPrice":88.5,"timestamp":1788292800000,"preClose":89.33,"halted":0,"volume":1429114,"hourTrading":{"tag":"盘后","latestPrice":88.5,"preClose":88.5,"latestTime":"19:30 EDT","volume":36962,"amount":3271128.49,"timestamp":1788305400665,"change":0,"changeRate":0,"amplitude":0},"delay":0,"changeRate":-0.009291391469830945,"floatShares":80977000,"shares":88173800,"eps":-2.009956,"marketStatus":"Closed","change":-0.83,"latestTime":"09-01 16:00:00 EDT","open":87.06,"high":90,"low":85,"amount":125199332.65364,"amplitude":0.055972,"askPrice":0,"askSize":0,"bidPrice":0,"bidSize":0,"shortable":3,"etf":0,"ttmEps":-2.009956,"tradingStatus":0,"nextMarketStatus":{"tag":"Pre-Mkt","tradingStatus":1,"beginTime":1788336000000},"marketStatusCode":5,"adr":0,"listingDate":1460001600000,"exchange":"NASDAQ","adjPreClose":89.33,"preHourTrading":{"tag":"盘前","latestPrice":88.38,"preClose":89.33,"latestTime":"09:29 EDT","volume":2630,"amount":232304.2706,"timestamp":1788269399999,"change":-0.95,"changeRate":-0.010635,"amplitude":0.062129},"postHourTrading":{"tag":"盘后","latestPrice":88.5,"preClose":88.5,"latestTime":"19:30 EDT","volume":36962,"amount":3271128.49,"timestamp":1788305400665,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":0.852281,"impliedVol":0.904,"impliedVolPercentile":0.7778},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SYRE\",,,,,undefined,":{"symbol":"SYRE","floatShares":80977000,"roa":"-19.81%","roe":"-22.98%","lyrEps":-1.975476,"volumeRatio":0.852281,"shares":88173800,"dividePrice":0,"high":90,"amplitude":0.055972,"preClose":89.33,"low":85,"week52Low":14.505,"pbRate":"8.17","week52High":110.175,"institutionHeld":0,"latestPrice":88.5,"eps":-2.009956,"divideRate":0,"volume":1429114,"delay":0,"ttmEps":-2.009956,"open":87.06,"prevYearClose":32.76,"prevWeekClose":90.36,"prevMonthClose":89.33,"prevQuarterClose":88.78,"fiveDayClose":107.36,"twentyDayClose":104.94,"sixtyDayClose":73.65},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/SYRE\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-04","symbol":"SYRE","fiscalQuarterEnding":"2026/06","expectedEps":-0.71,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1785816000000,"reportTimeType":"post","actualEps":-0.36},{"market":"US","date":"2026-05-05","symbol":"SYRE","fiscalQuarterEnding":"2026/03","expectedEps":-0.66,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777953600000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2026-02-19","symbol":"SYRE","fiscalQuarterEnding":null,"expectedEps":null,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1771477200000,"reportTimeType":"post","actualEps":null},{"market":"US","date":"2025-11-04","symbol":"SYRE","fiscalQuarterEnding":"2025/09","expectedEps":-0.68,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1762232400000,"reportTimeType":"post","actualEps":-0.15},{"market":"US","date":"2025-08-05","symbol":"SYRE","fiscalQuarterEnding":"2025/06","expectedEps":-0.73,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1754366400000,"reportTimeType":"post","actualEps":-0.49}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"SYRE\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"SYRE\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.5294,"buy":0.4118,"hold":0.0588,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.4118,"analysts":17,"updateTime":1785297600000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/SYRE\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"SYRE","date":"2026-08-31","current":-44.030815,"percent":0.056851,"low":-53.677585,"twenty":-18.049914,"median":-6.02901,"eighty":-4.083002,"high":-0.199399,"avg":-12.42881,"sd":13.451424,"marketCap":7967381134},"quantilePoints":[{"date":"2023-12-01","current":-1.902619,"twenty":-1.228042,"median":-0.216176,"eighty":-0.20611,"marketCap":560191990},{"date":"2023-12-08","current":-2.024974,"twenty":-2.048834,"median":-1.98164,"eighty":-0.890753,"marketCap":596217199},{"date":"2023-12-15","current":-1.815535,"twenty":-2.023412,"median":-1.966856,"eighty":-1.735642,"marketCap":534551743},{"date":"2023-12-22","current":-2.106706,"twenty":-2.023412,"median":-1.950531,"eighty":-1.82549,"marketCap":620281740},{"date":"2023-12-29","current":-2.507984,"twenty":-2.09023,"median":-1.996425,"eighty":-1.840422,"marketCap":738430643},{"date":"2024-01-05","current":-2.757559,"twenty":-2.278228,"median":-2.002935,"eighty":-1.873937,"marketCap":811913497},{"date":"2024-01-12","current":-2.567931,"twenty":-2.588728,"median":-2.024974,"eighty":-1.89995,"marketCap":756080936},{"date":"2024-01-19","current":-2.66458,"twenty":-2.653814,"median":-2.09023,"eighty":-1.902486,"marketCap":784537532},{"date":"2024-01-26","current":-3.303198,"twenty":-2.742878,"median":-2.292052,"eighty":-1.915254,"marketCap":972567189},{"date":"2024-02-02","current":-3.16373,"twenty":-3.116751,"median":-2.567931,"eighty":-1.947266,"marketCap":931503241},{"date":"2024-02-09","current":-2.89825,"twenty":-3.138772,"median":-2.61809,"eighty":-1.978684,"marketCap":853337655},{"date":"2024-02-16","current":-2.760005,"twenty":-3.112591,"median":-2.66458,"eighty":-1.997649,"marketCap":812633917},{"date":"2024-02-23","current":-2.496973,"twenty":-3.08641,"median":-2.66458,"eighty":-2.000865,"marketCap":735188752},{"date":"2024-03-01","current":-3.357028,"twenty":-3.117974,"median":-2.696389,"eighty":-2.009323,"marketCap":988416432},{"date":"2024-03-08","current":-4.14553,"twenty":-3.186241,"median":-2.748383,"eighty":-2.021849,"marketCap":1404464057},{"date":"2024-03-15","current":-4.473117,"twenty":-3.315921,"median":-2.757559,"eighty":-2.032927,"marketCap":1515447446},{"date":"2024-03-22","current":-4.253303,"twenty":-3.374155,"median":-2.84075,"eighty":-2.069838,"marketCap":1440976508},{"date":"2024-03-28","current":-3.948124,"twenty":-3.948124,"median":-2.884793,"eighty":-2.09023,"marketCap":1337584817},{"date":"2024-04-05","current":-3.822655,"twenty":-3.997689,"median":-2.933117,"eighty":-2.106706,"marketCap":1295077328},{"date":"2024-04-12","current":-4.169482,"twenty":-4.017483,"median":-2.950857,"eighty":-2.22293,"marketCap":1412578691},{"date":"2024-04-19","current":-3.844264,"twenty":-4.019298,"median":-3.071974,"eighty":-2.361175,"marketCap":1302398285},{"date":"2024-04-26","current":-3.508242,"twenty":-4.017483,"median":-3.149049,"eighty":-2.496973,"marketCap":1188557401},{"date":"2024-05-03","current":-4.312212,"twenty":-4.026871,"median":-3.180093,"eighty":-2.505537,"marketCap":1460934345},{"date":"2024-05-10","current":-4.183809,"twenty":-4.050631,"median":-3.290964,"eighty":-2.507984,"marketCap":1417432578},{"date":"2024-05-17","current":-4.180278,"twenty":-4.096445,"median":-3.334395,"eighty":-2.567931,"marketCap":1522561849},{"date":"2024-05-24","current":-3.614061,"twenty":-4.096445,"median":-3.364368,"eighty":-2.569154,"marketCap":1316331249},{"date":"2024-05-31","current":-4.872934,"twenty":-4.111605,"median":-3.38639,"eighty":-2.608303,"marketCap":1774844320},{"date":"2024-06-07","current":-4.694469,"twenty":-4.171641,"median":-3.527045,"eighty":-2.61809,"marketCap":1709842869},{"date":"2024-06-14","current":-4.393309,"twenty":-4.193693,"median":-3.59738,"eighty":-2.63375,"marketCap":1600152919},{"date":"2024-06-21","current":-3.360163,"twenty":-4.181695,"median":-3.573485,"eighty":-2.653814,"marketCap":1223855454},{"date":"2024-06-28","current":-3.277902,"twenty":-4.180281,"median":-3.545724,"eighty":-2.666048,"marketCap":1193893847},{"date":"2024-07-05","current":-3.553965,"twenty":-4.180278,"median":-3.545724,"eighty":-2.674367,"marketCap":1294442968},{"date":"2024-07-12","current":-4.13816,"twenty":-4.17596,"median":-3.564426,"eighty":-2.694186,"marketCap":1507221157},{"date":"2024-07-19","current":-4.113063,"twenty":-4.180278,"median":-3.593701,"eighty":-2.712782,"marketCap":1498080328},{"date":"2024-07-26","current":-4.387732,"twenty":-4.219183,"median":-3.614061,"eighty":-2.731867,"marketCap":1598121624},{"date":"2024-08-02","current":-3.651563,"twenty":-4.192391,"median":-3.674487,"eighty":-2.752053,"marketCap":1329990636},{"date":"2024-08-09","current":-6.773008,"twenty":-4.238871,"median":-3.689208,"eighty":-2.757559,"marketCap":1259650875},{"date":"2024-08-16","current":-7.111659,"twenty":-4.267009,"median":-3.707046,"eighty":-2.757559,"marketCap":1322633418},{"date":"2024-08-23","current":-6.972375,"twenty":-4.305721,"median":-3.744862,"eighty":-2.758537,"marketCap":1296729308},{"date":"2024-08-30","current":-7.851774,"twenty":-4.372067,"median":-3.796365,"eighty":-2.792303,"marketCap":1460280752},{"date":"2024-09-06","current":-7.655166,"twenty":-4.395693,"median":-3.839237,"eighty":-2.844176,"marketCap":1423715511},{"date":"2024-09-13","current":-8.038472,"twenty":-4.515004,"median":-3.909092,"eighty":-2.863261,"marketCap":1495003126},{"date":"2024-09-20","current":-8.260242,"twenty":-4.753435,"median":-3.923931,"eighty":-2.887484,"marketCap":1536248103},{"date":"2024-09-27","current":-7.800275,"twenty":-4.893011,"median":-3.931452,"eighty":-2.904612,"marketCap":1450702965},{"date":"2024-10-04","current":-7.980976,"twenty":-5.268067,"median":-3.990592,"eighty":-2.931282,"marketCap":1484309983},{"date":"2024-10-11","current":-7.857771,"twenty":-6.760445,"median":-4.004311,"eighty":-2.936176,"marketCap":1461396107},{"date":"2024-10-18","current":-8.969358,"twenty":-6.959266,"median":-4.01434,"eighty":-2.939112,"marketCap":1668130191},{"date":"2024-10-25","current":-9.530627,"twenty":-7.262959,"median":-4.019298,"eighty":-2.969942,"marketCap":1772515627},{"date":"2024-11-01","current":-9.303382,"twenty":-7.505129,"median":-4.04736,"eighty":-3.046528,"marketCap":1730252255},{"date":"2024-11-08","current":-9.47125,"twenty":-7.585076,"median":-4.070861,"eighty":-3.057293,"marketCap":2035390531},{"date":"2024-11-15","current":-6.988263,"twenty":-7.603794,"median":-4.087936,"eighty":-3.101825,"marketCap":1501791624},{"date":"2024-11-22","current":-7.566995,"twenty":-7.593388,"median":-4.106049,"eighty":-3.128495,"marketCap":1626162294},{"date":"2024-11-29","current":-7.766414,"twenty":-7.602508,"median":-4.133831,"eighty":-3.149049,"marketCap":1669017834},{"date":"2024-12-06","current":-7.397625,"twenty":-7.602508,"median":-4.146835,"eighty":-3.16373,"marketCap":1589764437},{"date":"2024-12-13","current":-6.589022,"twenty":-7.597044,"median":-4.169482,"eighty":-3.166361,"marketCap":1415994026},{"date":"2024-12-20","current":-6.517996,"twenty":-7.595055,"median":-4.180278,"eighty":-3.169847,"marketCap":1400730409},{"date":"2024-12-27","current":-6.466093,"twenty":-7.588386,"median":-4.182047,"eighty":-3.186241,"marketCap":1389576227},{"date":"2025-01-03","current":-6.651853,"twenty":-7.58308,"median":-4.215671,"eighty":-3.191991,"marketCap":1429496457},{"date":"2025-01-10","current":-6.135549,"twenty":-7.579794,"median":-4.247699,"eighty":-3.203592,"marketCap":1318541701},{"date":"2025-01-17","current":-5.632904,"twenty":-7.573901,"median":-4.253955,"eighty":-3.236074,"marketCap":1210522256},{"date":"2025-01-24","current":-5.900617,"twenty":-7.564263,"median":-4.27898,"eighty":-3.264517,"marketCap":1268054352},{"date":"2025-01-31","current":-6.280332,"twenty":-7.548513,"median":-4.304099,"eighty":-3.280514,"marketCap":1349655997},{"date":"2025-02-07","current":-6.187452,"twenty":-7.528128,"median":-4.345056,"eighty":-3.293411,"marketCap":1329695883},{"date":"2025-02-14","current":-6.26121,"twenty":-7.522652,"median":-4.382852,"eighty":-3.305947,"marketCap":1345546562},{"date":"2025-02-21","current":-5.815932,"twenty":-7.518271,"median":-4.394799,"eighty":-3.316941,"marketCap":1249855423},{"date":"2025-02-28","current":-5.708297,"twenty":-7.512359,"median":-4.473117,"eighty":-3.319102,"marketCap":1187428551},{"date":"2025-03-07","current":-5.647447,"twenty":-7.483663,"median":-4.605135,"eighty":-3.349687,"marketCap":1174770683},{"date":"2025-03-14","current":-5.227293,"twenty":-7.452562,"median":-4.749486,"eighty":-3.357028,"marketCap":1087371120},{"date":"2025-03-21","current":-5.264962,"twenty":-7.449529,"median":-4.833391,"eighty":-3.360163,"marketCap":1095206943},{"date":"2025-03-28","current":-5.198317,"twenty":-7.397625,"median":-4.89803,"eighty":-3.364368,"marketCap":1081343564},{"date":"2025-04-04","current":-3.706047,"twenty":-7.375771,"median":-4.833391,"eighty":-3.376602,"marketCap":770924425},{"date":"2025-04-11","current":-3.540883,"twenty":-7.371109,"median":-4.749486,"eighty":-3.378289,"marketCap":736567355},{"date":"2025-04-17","current":-3.671275,"twenty":-7.352984,"median":-4.694469,"eighty":-3.38477,"marketCap":763691357},{"date":"2025-04-25","current":-4.094327,"twenty":-7.328784,"median":-4.51381,"eighty":-3.412624,"marketCap":851693676},{"date":"2025-05-02","current":-4.378293,"twenty":-7.296115,"median":-4.473117,"eighty":-3.422161,"marketCap":910763726},{"date":"2025-05-09","current":-4.072986,"twenty":-7.269514,"median":-4.422481,"eighty":-3.450063,"marketCap":850985210},{"date":"2025-05-16","current":-4.384959,"twenty":-7.258044,"median":-4.393309,"eighty":-3.492778,"marketCap":916167055},{"date":"2025-05-23","current":-4.353184,"twenty":-7.252035,"median":-4.386346,"eighty":-3.506946,"marketCap":909528164},{"date":"2025-05-30","current":-4.491839,"twenty":-7.242247,"median":-4.381626,"eighty":-3.527827,"marketCap":938497873},{"date":"2025-06-06","current":-4.800924,"twenty":-7.228256,"median":-4.393309,"eighty":-3.543713,"marketCap":1003076183},{"date":"2025-06-13","current":-5.115786,"twenty":-7.156112,"median":-4.413455,"eighty":-3.545748,"marketCap":1068861565},{"date":"2025-06-20","current":-4.356073,"twenty":-7.062301,"median":-4.413455,"eighty":-3.549094,"marketCap":910131699},{"date":"2025-06-27","current":-4.627605,"twenty":-6.984824,"median":-4.413846,"eighty":-3.558149,"marketCap":966864047},{"date":"2025-07-03","current":-4.5525,"twenty":-6.978207,"median":-4.413846,"eighty":-3.566238,"marketCap":951172121},{"date":"2025-07-11","current":-4.610273,"twenty":-6.959266,"median":-4.434912,"eighty":-3.576816,"marketCap":963242833},{"date":"2025-07-18","current":-4.878917,"twenty":-6.905553,"median":-4.448509,"eighty":-3.590436,"marketCap":1019371645},{"date":"2025-07-25","current":-5.084011,"twenty":-6.899536,"median":-4.462257,"eighty":-3.592447,"marketCap":1062222673},{"date":"2025-08-01","current":-4.902026,"twenty":-6.889009,"median":-4.488402,"eighty":-3.59611,"marketCap":1024199930},{"date":"2025-08-08","current":-4.450911,"twenty":-6.843738,"median":-4.500505,"eighty":-3.597671,"marketCap":920510630},{"date":"2025-08-15","current":-4.924039,"twenty":-6.770823,"median":-4.509171,"eighty":-3.60188,"marketCap":1018360185},{"date":"2025-08-22","current":-4.900675,"twenty":-6.760445,"median":-4.52404,"eighty":-3.616232,"marketCap":1013528108},{"date":"2025-08-29","current":-4.883151,"twenty":-6.744059,"median":-4.5525,"eighty":-3.624946,"marketCap":1009904051},{"date":"2025-09-05","current":-4.962006,"twenty":-6.704732,"median":-4.610273,"eighty":-3.625072,"marketCap":1026212310},{"date":"2025-09-12","current":-4.731283,"twenty":-6.670975,"median":-4.650968,"eighty":-3.630649,"marketCap":978495552},{"date":"2025-09-19","current":-4.474275,"twenty":-6.670975,"median":-4.610273,"eighty":-3.651563,"marketCap":925342707},{"date":"2025-09-26","current":-4.558971,"twenty":-6.651853,"median":-4.590463,"eighty":-3.659766,"marketCap":942858985},{"date":"2025-10-03","current":-4.667031,"twenty":-6.651853,"median":-4.640746,"eighty":-3.671275,"marketCap":965207340},{"date":"2025-10-10","current":-6.182794,"twenty":-6.639187,"median":-4.66411,"eighty":-3.682866,"marketCap":1278688323},{"date":"2025-10-17","current":-6.495292,"twenty":-6.589022,"median":-4.675298,"eighty":-3.682866,"marketCap":1343317350},{"date":"2025-10-24","current":-8.382293,"twenty":-6.651853,"median":-4.679157,"eighty":-3.689208,"marketCap":1733575542},{"date":"2025-10-31","current":-9.090497,"twenty":-6.704732,"median":-4.696933,"eighty":-3.700564,"marketCap":1880042140},{"date":"2025-11-07","current":-11.662076,"twenty":-6.790267,"median":-4.714264,"eighty":-3.706047,"marketCap":1737287790},{"date":"2025-11-14","current":-11.787083,"twenty":-6.900444,"median":-4.731283,"eighty":-3.707046,"marketCap":1755909901},{"date":"2025-11-21","current":-12.224606,"twenty":-6.988263,"median":-4.745208,"eighty":-3.707046,"marketCap":1821087291},{"date":"2025-11-28","current":-15.625828,"twenty":-7.239349,"median":-4.751954,"eighty":-3.713244,"marketCap":2327763900},{"date":"2025-12-05","current":-17.454049,"twenty":-7.296115,"median":-4.772037,"eighty":-3.728167,"marketCap":2600112276},{"date":"2025-12-12","current":-17.896781,"twenty":-7.380142,"median":-4.779357,"eighty":-3.742192,"marketCap":2666065586},{"date":"2025-12-19","current":-17.433215,"twenty":-7.489402,"median":-4.800924,"eighty":-3.751648,"marketCap":2597008591},{"date":"2025-12-26","current":-17.214453,"twenty":-7.525937,"median":-4.815979,"eighty":-3.763383,"marketCap":2564419896},{"date":"2026-01-02","current":-17.063404,"twenty":-7.573901,"median":-4.841253,"eighty":-3.771122,"marketCap":2541918178},{"date":"2026-01-09","current":-15.698748,"twenty":-7.596248,"median":-4.85056,"eighty":-3.792677,"marketCap":2338626798},{"date":"2026-01-16","current":-17.235288,"twenty":-7.641035,"median":-4.868549,"eighty":-3.827277,"marketCap":2567523581},{"date":"2026-01-23","current":-17.756149,"twenty":-7.65516,"median":-4.878917,"eighty":-3.836222,"marketCap":2645115711},{"date":"2026-01-30","current":-17.49051,"twenty":-7.716495,"median":-4.891913,"eighty":-3.850233,"marketCap":2605543725},{"date":"2026-02-06","current":-17.157159,"twenty":-7.797537,"median":-4.900675,"eighty":-3.876725,"marketCap":2555884762},{"date":"2026-02-13","current":-18.146794,"twenty":-7.885881,"median":-4.903471,"eighty":-3.891573,"marketCap":2703309809},{"date":"2026-02-20","current":-23.527864,"twenty":-7.934432,"median":-4.916265,"eighty":-3.909092,"marketCap":3504922382},{"date":"2026-02-27","current":-21.83597,"twenty":-8.038472,"median":-4.931737,"eighty":-3.918816,"marketCap":3389008076},{"date":"2026-03-06","current":-20.540487,"twenty":-8.323214,"median":-4.953617,"eighty":-3.922049,"marketCap":3187945256},{"date":"2026-03-13","current":-20.449399,"twenty":-8.618907,"median":-4.962688,"eighty":-3.925813,"marketCap":3173808027},{"date":"2026-03-20","current":-21.41089,"twenty":-8.906386,"median":-4.973688,"eighty":-3.927002,"marketCap":3323034338},{"date":"2026-03-27","current":-24.0474,"twenty":-8.969358,"median":-4.994463,"eighty":-3.931452,"marketCap":3732228593},{"date":"2026-04-02","current":-24.745746,"twenty":-9.172768,"median":-5.075907,"eighty":-3.931939,"marketCap":3840614019},{"date":"2026-04-10","current":-26.198104,"twenty":-9.23713,"median":-5.085831,"eighty":-3.944911,"marketCap":4066024290},{"date":"2026-04-17","current":-38.738151,"twenty":-9.365612,"median":-5.125877,"eighty":-3.981637,"marketCap":6012277252},{"date":"2026-04-24","current":-38.48249,"twenty":-9.54815,"median":-5.141783,"eighty":-3.990939,"marketCap":5972597947},{"date":"2026-05-01","current":-41.378125,"twenty":-11.574571,"median":-5.163524,"eighty":-3.996385,"marketCap":6422009203},{"date":"2026-05-08","current":-35.378246,"twenty":-11.912235,"median":-5.194337,"eighty":-4.002987,"marketCap":6348095594},{"date":"2026-05-15","current":-36.612371,"twenty":-12.227731,"median":-5.199556,"eighty":-4.01025,"marketCap":6569540789},{"date":"2026-05-22","current":-35.96869,"twenty":-12.66317,"median":-5.24323,"eighty":-4.012918,"marketCap":6454041922},{"date":"2026-05-29","current":-34.899115,"twenty":-14.84662,"median":-5.263514,"eighty":-4.014565,"marketCap":6262122753},{"date":"2026-06-05","current":-37.982008,"twenty":-15.625828,"median":-5.295394,"eighty":-4.016676,"marketCap":6815301535},{"date":"2026-06-12","current":-39.0903,"twenty":-15.934177,"median":-5.346464,"eighty":-4.018572,"marketCap":7014168004},{"date":"2026-06-18","current":-42.342582,"twenty":-16.532126,"median":-5.375072,"eighty":-4.022327,"marketCap":7597741224},{"date":"2026-06-26","current":-42.913667,"twenty":-16.744637,"median":-5.470693,"eighty":-4.034149,"marketCap":7700213903},{"date":"2026-07-02","current":-43.020141,"twenty":-17.038402,"median":-5.524211,"eighty":-4.045526,"marketCap":7719318979},{"date":"2026-07-10","current":-47.79209,"twenty":-17.157159,"median":-5.623342,"eighty":-4.04736,"marketCap":8575573733},{"date":"2026-07-17","current":-46.12579,"twenty":-17.21862,"median":-5.641652,"eighty":-4.048014,"marketCap":8276581215},{"date":"2026-07-24","current":-49.002526,"twenty":-17.305083,"median":-5.684807,"eighty":-4.051257,"marketCap":8792768335},{"date":"2026-07-31","current":-49.742539,"twenty":-17.37592,"median":-5.758017,"eighty":-4.05376,"marketCap":8925552415},{"date":"2026-08-07","current":-50.967094,"twenty":-17.454049,"median":-5.886958,"eighty":-4.070861,"marketCap":9118930466},{"date":"2026-08-14","current":-50.193372,"twenty":-17.542596,"median":-5.928557,"eighty":-4.072986,"marketCap":8980497659},{"date":"2026-08-21","current":-53.120702,"twenty":-17.704063,"median":-5.957984,"eighty":-4.07743,"marketCap":9504249805},{"date":"2026-08-28","current":-46.135027,"twenty":-18.037414,"median":-6.00579,"eighty":-4.082736,"marketCap":8254386729},{"date":"2026-08-31","current":-44.530909,"twenty":-18.049914,"median":-6.02901,"eighty":-4.083002,"marketCap":7967381134}],"updateTime":1788314830545},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"SYRE\",pageSize:20,pageCount:1,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2663464017","title":"Analysts Offer Insights on Healthcare Companies: Revolution Medicines (RVMD) and Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2663464017","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2663464017?lang=en_us&edition=fundamental","pubTime":"2026-08-29 22:30","pubTimestamp":1788013830,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Revolution Medicines (RVMD) and Spyre Therapeutics (...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-revolution-medicines-rvmd-and-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-revolution-medicines-rvmd-and-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4137","LU0128526141.USD","LFSC","XLV","BBH","LU0029874061.USD","PTH","LU0320765992.SGD","XBI","IE0009354923.USD","IE00BFTCPJ56.SGD","LABU","IE00BJT1NW94.SGD","BK4588","BK4585","IE00BJJMRZ35.SGD","IE0009355771.USD","IDNA","BK4139","IE00B4R5TH58.HKD","BK4581","HCSG","LU0889565916.HKD","IE0002141913.USD","IE00B2B36J28.USD","RVMD","LU0109394709.USD","SYRE","CANC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662776456","title":"U.S. Research Roundup-CrowdStrike, Nvidia, Macerich","url":"https://stock-news.laohu8.com/highlight/detail?id=2662776456","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662776456?lang=en_us&edition=fundamental","pubTime":"2026-08-27 15:24","pubTimestamp":1787815457,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-CrowdStrike, Nvidia, MacerichAug 27 (Reuters)-Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including CrowdStrike, Nvi","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260827:nL4N44O0KN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["EOG","SCCO","NVDA","ATRC","DUOL","CHH","SNPS","XLK","ROKT","DOCN","NVDY","INTU","SHOC","SYRE","HEI","GAMR","CRM","HPQ","DY","DRH","EXR","METV","BBWI","DKS","GTLB","ESLG","IRM","MAC","SNOW","WSM","EFIV","VEEV","A","FFIN","RVMD","BRZE","FDS","CRMG","COPX","SJM","CELH","KMPR","TRGP","BWXT","P","DIPS","DTE","OKTA","ANF","CRWD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662749365","title":"Top Midday Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2662749365","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662749365?lang=en_us&edition=fundamental","pubTime":"2026-08-27 02:23","pubTimestamp":1787768612,"startTime":"0","endTime":"0","summary":"Electromed  Chief Executive Jim Cunniff plans to retire around April 2 after serving as president and CEO since 2023, it said late Tuesday, adding that the board plans to search for his successor.Shares declined 18%, with intraday trading volume rising to over 229,000 from a daily average of about 89,000.Greenland Mines  shares slumped 43% amid heavy trading after the company said it priced its public offering of 4 million shares for gross proceeds of about $20 million.Intraday trading volume catapulted to over 2.09 million from a daily average of about 174,000.Spyre Therapeutics  said late Tuesday its experimental rheumatoid arthritis drug SPY072 failed to meet the company's internal performance threshold needed to justify further stand-alone development, prompting a halt of its monotherapy RA program.Shares dropped 14% as intraday trading volume rose to over 1.96 million from a daily average of about 1.25 million.Price: 32.20, Change: -7.14, Percent Change: -18.15","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ELMD","GRML","BK4139","BK4082","SYRE","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662474530","title":"Spyre Therapeutics falls -13.2%","url":"https://stock-news.laohu8.com/highlight/detail?id=2662474530","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662474530?lang=en_us&edition=fundamental","pubTime":"2026-08-27 00:05","pubTimestamp":1787760324,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) is down -13.2%, or -$14.16 to $93.20. Published first on TheFly – the ultimate source for real-time, market-moving breaki...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-falls-13-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-falls-13-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4539","BK4007","BK4139","SYRE","LENZ","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662104247","title":"Spyre Therapeutics Down over 12%, on Pace for Largest Percent Decrease Since June 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2662104247","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662104247?lang=en_us&edition=fundamental","pubTime":"2026-08-26 22:35","pubTimestamp":1787754900,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics, Inc  is currently at $94.12, down $13.24 or 12.33%--Would be lowest close since July 16, 2026, when it closed at $94.12--On pace for largest percent decrease since June 17, 2024, when it fell 19.3%--Snaps a two day winning streak--Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61%--Up 187.3% year-to-date--Down 68.6% from its all-time closing high of $299.75 on April 8, 2016--Up 449.12% from 52 weeks ago , when it closed at $17.14--Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026--Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025--Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60--Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87%All data as of 10:32:24 AM ETSource: Dow Jones Market Data, FactSet","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","LENZ","SYRE","BK4007","BK4139","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662171137","title":"U.S. Stocks on the MOVE-Semtech, Donaldson, Meta","url":"https://stock-news.laohu8.com/highlight/detail?id=2662171137","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662171137?lang=en_us&edition=fundamental","pubTime":"2026-08-26 20:31","pubTimestamp":1787747476,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Semtech, Donaldson, MetaAugust 26 (Reuters)-U.S. stock index futures were little changed on Wednesday as investors stayed cautious ahead of AI bellwether Nvidia's earnings","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260826:nL6N44N0NW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0823421416.USD","NVDX","LU2100268510.USD","PLTY","LU1074936037.SGD","LU1868836757.USD","LU0823417737.USD","LU1923622291.USD","LU2491050154.USD","LU1992135399.USD","LU2108987350.USD","LU0234572021.USD","LU0395794307.EUR","NVD","3NVD.UK","LU0690374961.EUR","BK4581","LU2452424414.USD","LU2322448791.USD","LU0072462426.USD","LU0128525929.USD","LU0354030511.USD","LU0823414551.USD","NOW","IE00B19Z3581.USD","LU0079474960.USD","PLTW","LU1093756168.USD","LU0354030438.USD","LU1861127337.USD","NVD2.UK","LU0353189680.USD","LU0130517989.USD","BK4528","LU0347712357.USD","CNEQ","IETC","LU1057294990.SGD","LU1823568750.SGD","IE00B5TLWC47.USD","IE0004445239.USD","LU0994945656.USD","LU1633808545.USD","LU0211331839.USD","RSPC","LU2112291526.USD","SMTC","IE00B5949003.HKD","LU2361044865.SGD","SYRE","LU2111349929.HKD","BK4527","LU2097829019.USD","TEK","IE00BJTD4N35.SGD","LU2458330243.SGD","LU2417539215.USD","LU2294711713.HKD","PLYY","LU0823414478.USD","SG9999014559.SGD","IE00B4YYXB79.USD","LU0124676726.USD","IE00B19Z8W00.USD","LU1061106388.HKD","LU2125909916.SGD","SG9999001424.SGD","XDAT","LU1934455277.USD","LU2168563687.JPY","LU0082616367.USD","METQ","LU2461242641.AUD","LU2092627202.USD","LU0878866978.SGD","NVDA","LU1003077747.HKD","LU0912757837.SGD","IE0000B7K699.USD","JGRO","BK4505","LU0316494557.USD","HK0000306701.USD","IE00BQXX3C00.GBP","LU2471134523.USD","LU0345774391.USD","SG9999015341.SGD","CLSE","LU0234570918.USD","LU0187121727.USD","LU2506951875.HKD","VT","CLOD","LU0308772762.SGD","PLTR","LU0265550359.USD","LFGY","BK4023","LU0070302665.USD","BK4548","IE000F7OJYX1.SGD","METU","IE00BKVL7J92.USD","LU2750360641.GBP","LU1064131342.USD","LU1551013342.USD","LU2265009873.SGD","LU0882574055.USD","IE00BD6J9T35.USD","LU2720916845.USD","LU1712237335.SGD","LU1323610961.USD","LU1121112475.USD","LU2324357040.USD","LU2430703251.USD","LU0957791311.USD","LU0444971666.USD","LU0965509101.SGD","IE00BJJMRX11.SGD","LU0215105999.USD","LU1069347547.HKD","LU1236620834.HKD","LU2362540622.SGD","ANV","DCI","ZM","LU0070217475.USD","LU0950375773.USD","IE0002141913.USD","LU2237443978.SGD","LU2237443382.USD","ADBU","PLTL","LU2506951792.HKD","LU0238689110.USD","NVDL","LU0787776722.HKD","SHOC","LU0433182093.SGD","LU1267930227.SGD","LU2272731600.USD","LU1316542783.SGD","LTL","LU0006306889.USD","LU2023250504.SGD","BK4532","LU0784383803.USD","LU0823417653.USD","LU1720051108.HKD","LU2237957902.USD","IE00BDRTCR15.USD","LU0788109477.HKD","LU0985320562.USD","LU0511384066.AUD","LU1670710588.SGD","ILDR","LU1989764664.SGD","ESLG","LU2063271972.USD","NVDU","LU0149725797.USD","LU2491050071.SGD","LU2065169927.USD","LU1642822529.SGD","LU0106261372.USD","LU1059921491.USD","SG9999015952.SGD","LU1670756490.USD","LU0979878070.USD","SMETAmain","LU2602419157.SGD","IE00B3SWFQ91.USD","LU0965509010.AUD","LU2125154778.USD","IE00BZ9MQY76.HKD","LU1868836591.USD","IE000BZT7R73.USD","LU0353189763.USD","PLTI","SG9999002232.USD","PLTZ","IE00BJJMRZ35.SGD","NVDW","LU0175139822.USD","LU1923623000.USD","LU0345770993.USD","LU1066051498.USD","IE00BFSS8Q28.SGD","LU2462591350.SGD","LU0203202063.USD","ESUM","LU0942090050.USD","LU2413666426.HKD","LU0784385840.USD","LU2860962120.EUR","HK0000819398.USD","SOXY","LU0323240290.USD","LU0742534661.SGD","SNVDAmain","LU1564329032.USD","METW","LU2750360997.AUD","BK4598","IE0009356076.USD","IE00B7KXQ091.USD","IE00B1BXHZ80.USD","LU0012050646.USD","LU0158827781.USD","NVII","LU2023250843.SGD","LU0080751232.USD","SGXZ81514606.USD","LU2237443622.USD","IE000ITXATA3.USD","LU1815333072.USD","LU0205193047.USD","LU0208291251.USD","PLT","LU1069344957.HKD","LU2125154935.USD","LU0648000940.SGD","EYES","LU2191332357.HKD","SMH","GB00B4LPDJ14.GBP","LU0158827948.USD","LU0683600562.USD","LU0738911758.USD","SOXX","SG9999015358.SGD","LU0792757196.USD","LU1489326972.SGD","VOX","LU2458330169.SGD","IGV","LU0203347892.USD","LU1720051017.SGD","LU1935043536.SGD","LU2746668974.SGD","IE00B4JS1V06.HKD","LU0210533765.USD","LU2394011477.USD","LU1861559042.SGD","IE00BKPKM429.USD","LU0077335932.USD","LU1280957306.USD","LU2211815571.USD","IE00B7SZLL34.SGD","LU0426417589.USD","LU0323239441.USD","LU0786609619.USD","SG9999018857.SGD","CRMG","FTEC","CHPX","LU0417517546.SGD","LU1119994496.HKD","LU1564329115.USD","IE0001KFT4U8.USD","LU0130103400.USD","LU1127390331.HKD","LU0274383776.USD","LU2097344431.USD","LU1066053197.SGD","LU1267930490.SGD","NVC","IE00B19Z9Z06.USD","NVDG","LU0868494617.USD","SG9999014567.USD","LU2237443549.SGD","LU2272731865.HKD","LU2413666699.HKD","SG9999014880.SGD","BK4507","LU1301847155.USD","LU2430703178.SGD","LU0708995401.HKD","METV","LU0052756011.USD","IE00B894F039.SGD","AIFD","IE0004091025.USD","IE000Q6AESB8.SGD","LU0784384876.USD","LU1235294995.USD","IE00BMPRXR70.SGD","LU2506951958.HKD","HK0000306685.HKD","LU0130518102.USD","IE00BFSS7M15.SGD","IE0004086264.USD","LU0225283273.USD","LU2168564495.EUR","LU0477156953.USD","LU2456880835.USD","LU0861579265.USD","IE00BMPRXN33.USD","LU2462591277.SGD","LU1804176565.USD","SG9999013999.USD","LU2047632596.USD","LU1023059063.AUD","BK4607","LU0310800379.SGD","LU2236285917.USD","LU0980610538.SGD","LU1145028129.USD","OGIG","LU0323591593.USD","LU1941712348.USD","IE00BWXC8680.SGD","NVDQ","LU1242518931.SGD","BK4200","IE0002270589.USD","LU1974910355.USD","LU2065171311.SGD","LU1066051225.USD","BK4550","LU1670710661.SGD","LU0476273544.USD","LU2954938101.SGD","LU2250418816.HKD","LU0432979614.USD","PLTA","CRM","LU2247934214.USD","IE00B775H168.HKD","LU2028103732.USD","IE00BZ1G4Q59.USD","IE00BN29S564.USD","IE000WAW04H5.SGD","LU0552385451.USD","LU2210149790.SGD","LU0203345920.USD","LU2210150020.SGD","LU0823434583.USD","LU2264538146.SGD","IE00B3S45H60.SGD","LU0390134368.USD","BK4549","LU0314104364.USD","LU1670711040.USD","LU1989764748.USD","LU0266013472.USD","LU0642271901.SGD","LU0211328371.USD","LU0690374615.EUR","NVIW.SI","LU2462157665.USD","IE00B19Z3B42.SGD","NOWL","LU2326559502.SGD","IE0034235295.USD","LU0648001328.SGD","IE00BK4W5M84.HKD","IE0034235188.USD","LU2505996681.GBP","LU1093756325.SGD","LU0310799852.SGD","LU1429558221.USD","GUNZ","NVDS.UK","LU2237957811.SGD","BK4538","LU0130102774.USD","LU2272731782.SGD","NOWX","LU1043141123.HKD","LU1242518857.USD","IE00BFTCPJ56.SGD","LU1670628061.USD","BK4612","LU0795875086.SGD","LU1496350171.SGD","LU2237438978.USD","LU1941712264.USD","LU1066051811.HKD","BK4535","LU0868494708.USD","LU1880398471.USD","SOCL","LU0029864427.USD","LU2168564222.USD","BBWI","LU0342679015.USD","LU2360032135.SGD","LU2357125470.USD","FBL","LU0061474705.USD","LU2148611432.USD","LU0345769631.USD","CHAT","LU0154236417.USD","LU0494093205.USD","LU2317271919.USD","LU2471134952.CNY","LU2491049909.HKD","SNPE","LU2552382215.SGD","LU2361045086.USD","BK4139","LU1645745479.HKD","LU1791710400.SGD","IE00BQXX3D17.EUR","LU1267930573.SGD","LU1670627923.USD","IE00BHPRN162.USD","SOXQ","LU1564329461.SGD","SG9999001176.SGD","LU0251132253.USD","LU2125909247.SGD","LU1400636657.SGD","IE00BFXG0V08.USD","LU2505996509.AUD","INTU","LU0094547139.USD","NULC","LU0964807845.USD","LU0466842654.USD","DIPS","LU0053666078.USD","SG9999015945.SGD","BK4547","BK4551","LU2756315318.SGD","LU0889566641.SGD","LU2065170008.USD","GB00B4QBRK32.GBP","IXN","IE000SO60NU8.SGD","LU0726765562.USD","GAMR","SGXZ99366536.SGD","LU2362541513.USD","LU1699723380.USD","LU2065171402.SGD","LU0823434740.USD","LU1732799900.SGD","HK0000320264.USD","LU0133085943.USD","LU0276348264.USD","LU1116320901.HKD","NVYY","LU0096362180.USD","LU2360107168.USD","IE00BMPRXQ63.HKD","LU3102509885.SGD","IE0004445015.USD","LU0265550946.USD","SG9999014914.USD","LU2290526834.HKD","LU2087625088.SGD","XLC","IE00B19Z8X17.USD","BK4566","IE00BJTD4V19.USD","LU0128525689.USD","PLTD","IE00B2B36J28.USD","LU2403377893.USD","BSX","WISE","LU0820562030.AUD","LU0444973449.USD","SGXZ57979304.SGD","LU2764263039.SGD","TRFK","TRUP","LU2133065610.SGD","LU0823421333.USD","LU1791710582.SGD","HK0000304805.HKD","BK4141","LU2347655073.USD","IE00B19Z9505.USD","LU0143551892.USD","SG9999014542.SGD","LU0072461881.USD","EFIV","LU0251131958.USD","LU0048573561.USD","LU1623119135.USD","LU0472753341.HKD","SG9999014906.USD","LU2347655156.SGD","METG","LU2106854487.HKD","LU1880398554.USD","LU1732800096.USD","PLOO","LU1934455194.USD","LU1721428933.USD","LU2249611893.SGD","LU1236620750.USD","LU0426412945.USD","BK4561","LU1496350502.SGD","LU1803068979.SGD","BK4592","IE00BQXX3F31.USD","GXPC","LU1366333091.USD","LU1983299246.USD","LU0345774631.USD","LU0965509283.SGD","IE00B4R5TH58.HKD","BK4524","PLTG","LU0211327993.USD","LU2125909593.SGD","LU2097344357.USD","LU1366192091.USD","BK4504","LU0784385170.HKD","SNVD.UK","SG9999017495.SGD","TTEQ","LU1935042991.SGD","LU0251142724.SGD","LU2242650005.HKD","LU2083900584.USD","LU1629891620.HKD","TYLG","LU1979441026.SGD","LU1992135472.HKD","LU2286300806.USD","LU0048584097.USD","LU0267386448.USD","CMAG","LU1291159041.SGD","IE00BKDWB100.SGD","LU0640476718.USD","LU1923622614.USD","NVDY","LU2404859667.USD","LU1244550494.USD","LU1868836914.USD","LU0256863811.USD","LU0057025933.USD","LU1244550221.USD","LU1571399168.USD","LU1821325948.USD","LU2023250330.USD","TRUC","BHVN","LU0205194284.USD","LU1868837300.USD","LU2361044949.HKD","LU0348723411.USD","LU2487616109.SGD","BK4554","LFSC","LU2089284900.SGD","LU0689472784.USD","LU2471134879.HKD","LU0949170426.SGD","LU0553294199.USD","LU2357305700.SGD","IE0009355771.USD","LU2404859741.USD","BK4525","LU2931357623.SGD","ADBG","LU1951198990.SGD","FBYY","LU1983260115.SGD","ADBE","BK4097","LU2242649171.HKD","IE00BYXW3230.USD","LU0068578508.USD","BK4161","BK4162","LU2125909759.SGD","LU1035773651.USD","NVDS","BK4614","SG9999014898.SGD","BK4567","LU2362541273.HKD","LU1244550577.SGD","BK4587","LU0056508442.USD","LU0210536198.USD","LU2095319765.USD","LU1670711123.USD","LU0162691827.USD","LU2271345857.HKD","LU1935042488.USD","NVD3.UK","IE0005OL40V9.USD","LU1400636574.HKD","LU2054465674.USD","SG9999015978.USD","FCOM","LU0107464264.USD","LU0157215616.USD","LU1035775433.USD","THMR","IE00BYQQ9H92.USD","FAI","LU1861558580.USD","LU1267930730.SGD","LU0557290698.USD","07788","LU1037948541.HKD","PTIR","IE00BZ199S13.USD","SG9999002224.SGD","LU1400636491.USD","LU1201861165.SGD","IE000W1ABFV2.USD","BK4579","LU1564329628.SGD","LU0345770308.USD","LU2746668461.USD","LU2023251221.USD","AIPI","LU1868837136.USD","LU2552382058.USD","LU2506952170.USD","LU1935043023.USD","LU1691799644.USD","LU0109391861.USD","LU0061474960.USD","LU1935042215.USD","LU2089283258.USD","LU0943347566.SGD","BK4585","LU2168564065.EUR","BK4588","SG9999001077.SGD","BK4082","LU0320765489.SGD","LU0719512351.SGD","LU0672654240.SGD","XLK","IE00BK4W5L77.USD","BK4543","LU0138981039.USD","IE00BDCRKT87.USD","LU0203201768.USD","LU1548497426.USD","LU0109392836.USD","LU2237443895.HKD","LU2506952097.USD","ARTY","IE00B19Z9P08.USD","LU2360106780.USD","USXF","BK4077","LU0011850046.USD","LU2433249047.HKD","SGXZ51526630.SGD","NVDD","BK4613","LU0310800965.SGD","FBX","AGOX","LU2552382132.HKD","LU0689626769.HKD","SG9999000418.SGD","FDTX","IE000KEQY171.SGD","LU1551013425.SGD","METD","2NVD.UK","PLTU","IE00BJJMRY28.SGD","LU0889565833.HKD","ROM","LU0289961442.SGD","LU2237443465.HKD","LU0127658192.USD","SG9999015986.USD","LU1989772840.SGD","LU1917777945.USD","LU2213496289.HKD","LU1815336760.USD","IE0003U64NQ7.SGD","LU2764262908.HKD","LU1951200564.SGD","LU2381873111.SGD","BK4529","LU2463028550.USD","LU2322448957.HKD","LU0320765059.SGD","LU2089985449.USD","IE00B1XK9C88.USD","LU0114720955.EUR","BK4534","LU2756315664.SGD","SGXZ23171101.USD","SG9999018865.SGD","LU0170899867.USD","LU1043141396.HKD","USD","LU1989772923.USD","NVDB","LU0210528500.USD","LU2087621335.USD","SG9999001176.USD","LU1232071149.USD","IE000MB6IJN5.SGD","LU0882574139.USD","LU1046421795.USD","LU2092937148.SGD","LU1201861249.SGD","SGXZ31699556.SGD","SPLTRmain","HK0000914660.USD","LU1435385759.SGD","LU0985489474.SGD","LU0820561909.HKD","LU0256863902.USD","LU1814569148.SGD","LU0174119429.USD","LU1084165304.USD","LU2420271590.USD","LU2764263203.CNY","IE0034235303.USD","LU0823416689.USD","LU0096364046.USD","LU0054578231.USD","BK4533","LU1674673428.USD","LU0069063385.USD","LU2168564149.EUR","LU1914381329.SGD","IE000YTNTUN2.SGD","BK4605","TTXU","LU0708994859.HKD","LU0477156797.USD","LU2999663052.SGD","LU0345769128.USD","LU1934455863.HKD","HK0000532082.HKD","LU0061475181.USD","LU0528227936.USD","FBY","LU0965508806.USD","LU0957808578.USD","LU1037948897.HKD","LU2077746001.SGD","VGT","ABFL","LU0122379950.USD","LU1839511570.USD","LU1153585028.USD","BK4503","LU1267930813.SGD","SG9999004303.SGD","SPTE","LU2637965513.SGD","LU2430703095.HKD","LU0345768153.USD","NVDO","LU1261432733.SGD","IE0009G5SDU7.USD","LU1144417596.USD","LU1989771016.USD","GB00BDT5M118.USD","LU0097036916.USD","LU1778281490.HKD","LU2279689827.SGD","LU1697837992.HKD","LU0795875169.SGD","LU0289739343.SGD","LU1718418525.SGD","LU2244417387.USD","HK0000304797.USD","LU0820561818.USD","LU0198837287.USD","IE00B775SV38.USD","LU1861215975.USD","BK4107","LU2473716301.USD","LU1674673691.USD","LU1852331112.SGD","META","IE00B3M56506.USD","SHLD","LU0081259029.USD","LU2896262040.SGD","LU2543165471.USD","LU0345768740.USD","LU1861220033.SGD","LU2592432038.USD","LU2471134796.USD","LU0949170772.SGD","SMHX","SG9999014575.USD","LU0545039389.USD","07388","LU0106261612.USD","SGXZ80539844.SGD","LU0289960550.SGD","LU0724617625.USD","BK4608","LU1202635105.USD","SMTG","LU1988902786.USD","LU0661504455.SGD","HK0000320223.HKD","HK0000914686.HKD","IE00BJT1NW94.SGD","IE00BJLML261.HKD","LU1116320737.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662164967","title":"Spyre Therapeutics (SYRE) Gets a Buy from LifeSci Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2662164967","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662164967?lang=en_us&edition=fundamental","pubTime":"2026-08-26 19:55","pubTimestamp":1787745337,"startTime":"0","endTime":"0","summary":"In a report released today, Sam Slutsky from LifeSci Capital maintained a Buy rating on Spyre Therapeutics, with a price target of $116.00. Slutsky...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-gets-a-buy-from-lifesci-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-gets-a-buy-from-lifesci-capital-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","LFSC","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662239718","title":"Analysts Offer Insights on Healthcare Companies: Solventum Corporation (SOLV), Argenx Se (ARGX) and Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2662239718","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662239718?lang=en_us&edition=fundamental","pubTime":"2026-08-26 18:50","pubTimestamp":1787741417,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on Solventum Corporation (SOLV), Argenx Se (ARGX) and S...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-solventum-corporation-solv-argenx-se-argx-and-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-solventum-corporation-solv-argenx-se-argx-and-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4198","LU0029874061.USD","TBXU","LU0128526141.USD","LFSC","LU0889565916.HKD","XBI","IE00BJJMRZ35.SGD","BK4137","IE0002141913.USD","SYRE","LU0823416689.USD","BK4505","FMED","LU0320765992.SGD","XLV","LABU","LU1983260115.SGD","IE00B4R5TH58.HKD","IE00BFTCPJ56.SGD","BK4139","IE00BJT1NW94.SGD","BK4581","IE0034235188.USD","SOLV","IE0009355771.USD","IBB","ARGX","BK4585","LU0109394709.USD","BK4588","LU2324357040.USD","HCSG","IE00B2B36J28.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662979105","title":"Spyre Therapeutics Reports Phase 2 Skyway RA Data for Spy072 Shows Statistically Significant Benefit vs Placebo","url":"https://stock-news.laohu8.com/highlight/detail?id=2662979105","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662979105?lang=en_us&edition=fundamental","pubTime":"2026-08-26 17:30","pubTimestamp":1787736639,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics reports Phase 2 SKYWAY RA data for SPY072 shows statistically significant benefit vs placeboSpyre Therapeutics reported topline Phase 2 SKYWAY rheumatoid arthritis sub-study results","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260826:nNDL2xmQmj:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LFSC","BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662799910","title":"Spyre Therapeutics Shares Down 12.4% Premarket After Co's Experimental Drug Fails to Meet Threshold for Monotherapy Development in Rheumatoid Arthritis","url":"https://stock-news.laohu8.com/highlight/detail?id=2662799910","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662799910?lang=en_us&edition=fundamental","pubTime":"2026-08-26 16:57","pubTimestamp":1787734667,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260826:nL4N44N0KB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","LFSC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662762356","title":"Spyre Therapeutics Inc : Btig Cuts Target Price to $121 from $132","url":"https://stock-news.laohu8.com/highlight/detail?id=2662762356","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662762356?lang=en_us&edition=fundamental","pubTime":"2026-08-26 12:34","pubTimestamp":1787718880,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260826:nFWN44N05M:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","LFSC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662768622","title":"Stocks to Watch: Intuit, Spyre Therapeutics, Zoom Communications, nCino","url":"https://stock-news.laohu8.com/highlight/detail?id=2662768622","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662768622?lang=en_us&edition=fundamental","pubTime":"2026-08-26 07:05","pubTimestamp":1787699100,"startTime":"0","endTime":"0","summary":"Intuit projected that sales growth would slow in the year ahead, weighed down by expected declines in the company's desktop business. The company may also accept short-term trade-offs in its business as it looks to boost TurboTax customers, its CFO told The Wall Street Journal. Shares fell 9.8% to $322.57 in after-hours trading on Tuesday.Spyre Therapeutics said it will not prioritize developing one of its drug candidates as a monotherapy for rheumatoid arthritis after results from a trial missed its internal targets. The stock slid 11% to $95.09 after the bell.Zoom Communications issued guidance for third-quarter adjusted earnings per share that missed Wall Street expectations. Shares were down 3.9% at $97.00.NCino projected third-quarter revenue in a range with a midpoint below analyst expectations. The stock was down 5.6% at $19.65.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0994945656.USD","LU1803068979.SGD","LU1861558580.USD","LU2089284900.SGD","LU0345774391.USD","BK4581","BK4585","LU2210149790.SGD","LU0965509283.SGD","BK4551","BK4505","LU1235294995.USD","LU0511384066.AUD","LU0289961442.SGD","IE00B19Z8W00.USD","SG9999002232.USD","IE0009356076.USD","LU2265009873.SGD","LU2063271972.USD","BK4528","LU0342679015.USD","LU0949170772.SGD","LU1674673691.USD","LU0719512351.SGD","LU2095319765.USD","SG9999002224.SGD","LU1861559042.SGD","LFSC","LU0011850046.USD","LU1046421795.USD","LU2065170008.USD","LU0965509010.AUD","LU0097036916.USD","LU0289739343.SGD","BK4535","LU1236620750.USD","LU0965509101.SGD","LU1674673428.USD","LU0124676726.USD","INTU","LU1043141123.HKD","LU1043141396.HKD","BK4588","BK4548","IE00B19Z9505.USD","LU1778281490.HKD","IE00B19Z8X17.USD","LU1934455277.USD","LU0889565833.HKD","LU0738911758.USD","LU2065169927.USD","LU0965508806.USD","LU1366333091.USD","BK4567","LU0157215616.USD","LU0109392836.USD","LU1236620834.HKD","LU0957791311.USD","LU2210150020.SGD","GB00BDT5M118.USD","BK4613","BK4139","LU1815333072.USD","IE00BQXX3D17.EUR","LU1037948541.HKD","BK4608","LU2089283258.USD","LU1121112475.USD","LU1037948897.HKD","LU2065171402.SGD","LU0082616367.USD","LU0640476718.USD","NCNO","LU0661504455.SGD","LU0158827948.USD","LU1823568750.SGD","LU1934455863.HKD","LU0689626769.HKD","IE00B5949003.HKD","IE00BQXX3F31.USD","BK4554","LU2065171311.SGD","LU1280957306.USD","LU2023251221.USD","BK4533","LU0861579265.USD","LU0266013472.USD","ZM","LU0823434740.USD","BK4023","IE00BQXX3C00.GBP","LU0426412945.USD","LU1804176565.USD","BK4534","LU0426417589.USD","BK4525","BK4532","LU1934455194.USD","LU0061474960.USD","LU0345774631.USD","SYRE","LU0823434583.USD","SG9999001424.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662776851","title":"Spyre Therapeutics Stock (SYRE) Tumbles 14% in After-Hours – Here’s What Spooked Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2662776851","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662776851?lang=en_us&edition=fundamental","pubTime":"2026-08-26 06:51","pubTimestamp":1787698276,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics ($SYRE) fell as much as 14% in after‑hours trading on Tuesday after the company said it will stop developing its rheumatoid arth...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/spyre-therapeutics-stock-syre-tumbles-14-in-after-hours-heres-what-spooked-investors?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/spyre-therapeutics-stock-syre-tumbles-14-in-after-hours-heres-what-spooked-investors?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SYRE","ISBC","BK4211","LFSC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662675221","title":"Spyre Therapeutics Won't Prioritize Rheumatoid Arthritis Monotherapy After Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2662675221","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662675221?lang=en_us&edition=fundamental","pubTime":"2026-08-26 05:00","pubTimestamp":1787691600,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics will not prioritize the use of its SPY072 drug candidate as a monotherapy to treat rheumatoid arthritis, saying that results from a phase 2 trial did not meet the company's threshold.Shares of the biotechnology company fell on the news, losing 13% in after-hours trading to $93.50.A substudy of the drug to treat rheumatoid arthritis, part of a broader phase 2 study focusing on rheumatic diseases, showed that high and low doses both had statistically significant benefits over a placebo on certain endpoints, Spyre said. The low dose demonstrated a statistically significant benefit on the study's primary endpoint, the company added.But the magnitude of the results missed the company's targets, it said.\"The results provide proof-of-mechanism for TL1A in RA and support its potential in other autoimmune diseases and as a combination component, but did not meet the Company's internal bar to prioritize advancement of SPY072 in RA,\" the company said. SPY072 is designed to inhi","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4007","LFSC","LENZ","BK4539","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662754700","title":"Spyre Therapeutics announces results from RA sub-study of SKYWAY basket trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2662754700","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662754700?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:05","pubTimestamp":1787688312,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) announced results from the RA sub-study of its Phase 2 SKYWAY basket trial evaluating SPY072 in rheumatic diseases. Both ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-announces-results-from-ra-sub-study-of-skyway-basket-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-announces-results-from-ra-sub-study-of-skyway-basket-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","LFSC","BK4139","SYRE","RA","BK4539","LENZ"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662981754","title":"Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-Study of the Skyway Phase 2 Trial of Spy072","url":"https://stock-news.laohu8.com/highlight/detail?id=2662981754","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662981754?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:01","pubTimestamp":1787688060,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260825:nTUA3HCVK8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LFSC","BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662754989","title":"Spyre Therapeutics - Spy072 Well Tolerated with Adverse Event Rates Comparable to Placebo","url":"https://stock-news.laohu8.com/highlight/detail?id=2662754989","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662754989?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:01","pubTimestamp":1787688060,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260825:nTUA3HCVK8:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LFSC","BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662754982","title":"Spyre Therapeutics Inc: Spy072 in Combination with Il17-a/F in Hidradenitis Suppurativa (Hs) in Late 2027 or Early 2028","url":"https://stock-news.laohu8.com/highlight/detail?id=2662754982","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662754982?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:01","pubTimestamp":1787688060,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260825:nTUA3HCVK8:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","LFSC","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662549867","title":"Spyre Therapeutics - Topline Data for Spy072 in Psa and Axspa Expected Q4 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2662549867","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662549867?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:01","pubTimestamp":1787688060,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260825:nTUA3HCVK8:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","LFSC","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662549807","title":"Spyre Therapeutics Inc - Magnitude of Effect Did not Meet Company's Target to Prioritize Monotherapy Development of Spy072 in Rheumatoid Arthritis","url":"https://stock-news.laohu8.com/highlight/detail?id=2662549807","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662549807?lang=en_us&edition=fundamental","pubTime":"2026-08-26 04:01","pubTimestamp":1787688060,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260825:nTUA3HCVK8:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LFSC","BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":9,"pageCount":1,"totalSize":175,"code":"91000000","status":"200"}]}}