US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

SPYRE THERAPEUTICS INC

85.84

-2.6600-3.01%

Volume:689.54K

Turnover:59.95M

Market Cap:7.57B

PE:-42.71

High:90.18

Open:88.05

Low:85.00

Close:88.50

52wk High:110.18

52wk Low:14.51

Shares:88.17M

Float Shares:80.98M

Volume Ratio:0.62

T/O Rate:0.85%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:7.93

PE(LYR):-43.45

Loading ...

Overview Company News Filings

Spyre Therapeutics Inc : Wedbush Raises Target Price to $80 From $65

THOMSON REUTERS

Spyre Therapeutics, Inc. : Wells Fargo Raises Target Price to $90 From $50

THOMSON REUTERS

Spyre Therapeutics Inc : Deutsche Bank Raises Target Price to $88 From $55

THOMSON REUTERS

Spyre Therapeutics Inc : Jefferies Raises Target Price to $85 From $47

THOMSON REUTERS

BUZZ-Spyre drops on equity offering launch following inflammatory bowel drug trial

BRIEF-Spyre Therapeutics Inc - Suspends And Terminates ATM Prospectus For At-The-Market Offering Effective April 13, 2026 - SEC Filing

Spyre Therapeutics Launches $300 Million Stock Offering

MT Newswires Live

Spyre Therapeutics launches $300 million common stock offering

Spyre Therapeutics Announces Proposed Public Offering of Its Common Stock

THOMSON REUTERS

Spyre Therapeutics Inc - Suspends and Terminates Atm Prospectus for at-the-Market Offering Effective April 13, 2026 - SEC Filing

THOMSON REUTERS

Spyre data ‘exceptional,’ but combos could enable ‘dominance,’ says TD Cowen

Analysts’ Top Healthcare Picks: Oruka Therapeutics (ORKA), Spyre Therapeutics (SYRE)

Leerink sees Spyre’s SPY001 Phase 2 Data as incrementally positive for Oruka

Top Midday Gainers

MT Newswires Live

BUZZ-U.S. STOCKS ON THE MOVE-Conagra, Oracle, Replimune

Spyre Therapeutics rises 24.2%

BUZZ-U.S. STOCKS ON THE MOVE-Allogene Therapeutics, Adobe, Williams-Sonoma

Spyre Therapeutics Up Nearly 25%, on Track for Highest Close Since April 2022 -- Data Talk

Sector Update: Health Care

MT Newswires Live

Spyre Therapeutics Shares Surge 23% in Pre-Market Trading

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://au1.tigermoments.com/stock/SYRE/news?page=7"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"SYRE","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SYRE\",,,,,undefined,":{"symbol":"SYRE","market":"US","secType":"STK","nameCN":"SPYRE THERAPEUTICS INC","latestPrice":85.84,"timestamp":1788370464300,"preClose":88.5,"halted":0,"volume":689544,"delay":0,"changeRate":-0.030056497175141205,"floatShares":80977000,"shares":88173800,"eps":-2.009956,"marketStatus":"Trading","change":-2.66,"latestTime":"09-02 13:34:25 EDT","open":88.05,"high":90.18,"low":85,"amount":59948645.0652,"amplitude":0.058531,"askPrice":86.01,"askSize":204,"bidPrice":85.83,"bidSize":1,"shortable":3,"etf":0,"ttmEps":-2.009956,"tradingStatus":2,"nextMarketStatus":{"tag":"Post-Mkt","tradingStatus":3,"beginTime":1788379200000},"marketStatusCode":2,"adr":0,"listingDate":1460001600000,"exchange":"NASDAQ","adjPreClose":88.5,"preHourTrading":{"tag":"盘前","latestPrice":88.99,"preClose":88.5,"latestTime":"09:29 EDT","volume":1831,"amount":161762.38657,"timestamp":1788355799999,"change":0.49,"changeRate":0.005537,"amplitude":0.045198},"postHourTrading":{"tag":"盘后","latestPrice":88.5,"preClose":88.5,"latestTime":"19:30 EDT","volume":36962,"amount":3271128.49,"timestamp":1788305400665,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":0.617376,"impliedVol":0.7147,"impliedVolPercentile":0.377},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SYRE\",,,,,undefined,":{"symbol":"SYRE","floatShares":80977000,"roa":"-19.81%","roe":"-22.98%","lyrEps":-1.975476,"volumeRatio":0.617376,"shares":88173800,"dividePrice":0,"high":90.18,"amplitude":0.058531,"preClose":88.5,"low":85,"week52Low":14.505,"pbRate":"7.93","week52High":110.175,"institutionHeld":0,"latestPrice":85.84,"committee":-0.990244,"eps":-2.009956,"divideRate":0,"volume":689544,"delay":0,"ttmEps":-2.009956,"open":88.05,"prevYearClose":32.76,"prevWeekClose":90.36,"prevMonthClose":89.33,"prevQuarterClose":88.78,"fiveDayClose":93.605,"twentyDayClose":104.35,"sixtyDayClose":72},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/SYRE\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-04","symbol":"SYRE","fiscalQuarterEnding":"2026/06","expectedEps":-0.71,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1785816000000,"reportTimeType":"post","actualEps":-0.36},{"market":"US","date":"2026-05-05","symbol":"SYRE","fiscalQuarterEnding":"2026/03","expectedEps":-0.66,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777953600000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2026-02-19","symbol":"SYRE","fiscalQuarterEnding":null,"expectedEps":null,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1771477200000,"reportTimeType":"post","actualEps":null},{"market":"US","date":"2025-11-04","symbol":"SYRE","fiscalQuarterEnding":"2025/09","expectedEps":-0.68,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1762232400000,"reportTimeType":"post","actualEps":-0.15},{"market":"US","date":"2025-08-05","symbol":"SYRE","fiscalQuarterEnding":"2025/06","expectedEps":-0.73,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1754366400000,"reportTimeType":"post","actualEps":-0.49}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"SYRE\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"SYRE\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.5294,"buy":0.4118,"hold":0.0588,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.4118,"analysts":17,"updateTime":1785297600000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/SYRE\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"SYRE","date":"2026-09-01","current":-42.707403,"percent":0.058224,"low":-53.677585,"twenty":-18.109292,"median":-6.039937,"eighty":-4.083268,"high":-0.199399,"avg":-12.474733,"sd":13.495428,"marketCap":7876562159},"quantilePoints":[{"date":"2023-12-01","current":-1.902619,"twenty":-1.228042,"median":-0.216176,"eighty":-0.20611,"marketCap":560191990},{"date":"2023-12-08","current":-2.024974,"twenty":-2.048834,"median":-1.98164,"eighty":-0.890753,"marketCap":596217199},{"date":"2023-12-15","current":-1.815535,"twenty":-2.023412,"median":-1.966856,"eighty":-1.735642,"marketCap":534551743},{"date":"2023-12-22","current":-2.106706,"twenty":-2.023412,"median":-1.950531,"eighty":-1.82549,"marketCap":620281740},{"date":"2023-12-29","current":-2.507984,"twenty":-2.09023,"median":-1.996425,"eighty":-1.840422,"marketCap":738430643},{"date":"2024-01-05","current":-2.757559,"twenty":-2.278228,"median":-2.002935,"eighty":-1.873937,"marketCap":811913497},{"date":"2024-01-12","current":-2.567931,"twenty":-2.588728,"median":-2.024974,"eighty":-1.89995,"marketCap":756080936},{"date":"2024-01-19","current":-2.66458,"twenty":-2.653814,"median":-2.09023,"eighty":-1.902486,"marketCap":784537532},{"date":"2024-01-26","current":-3.303198,"twenty":-2.742878,"median":-2.292052,"eighty":-1.915254,"marketCap":972567189},{"date":"2024-02-02","current":-3.16373,"twenty":-3.116751,"median":-2.567931,"eighty":-1.947266,"marketCap":931503241},{"date":"2024-02-09","current":-2.89825,"twenty":-3.138772,"median":-2.61809,"eighty":-1.978684,"marketCap":853337655},{"date":"2024-02-16","current":-2.760005,"twenty":-3.112591,"median":-2.66458,"eighty":-1.997649,"marketCap":812633917},{"date":"2024-02-23","current":-2.496973,"twenty":-3.08641,"median":-2.66458,"eighty":-2.000865,"marketCap":735188752},{"date":"2024-03-01","current":-3.357028,"twenty":-3.117974,"median":-2.696389,"eighty":-2.009323,"marketCap":988416432},{"date":"2024-03-08","current":-4.14553,"twenty":-3.186241,"median":-2.748383,"eighty":-2.021849,"marketCap":1404464057},{"date":"2024-03-15","current":-4.473117,"twenty":-3.315921,"median":-2.757559,"eighty":-2.032927,"marketCap":1515447446},{"date":"2024-03-22","current":-4.253303,"twenty":-3.374155,"median":-2.84075,"eighty":-2.069838,"marketCap":1440976508},{"date":"2024-03-28","current":-3.948124,"twenty":-3.948124,"median":-2.884793,"eighty":-2.09023,"marketCap":1337584817},{"date":"2024-04-05","current":-3.822655,"twenty":-3.997689,"median":-2.933117,"eighty":-2.106706,"marketCap":1295077328},{"date":"2024-04-12","current":-4.169482,"twenty":-4.017483,"median":-2.950857,"eighty":-2.22293,"marketCap":1412578691},{"date":"2024-04-19","current":-3.844264,"twenty":-4.019298,"median":-3.071974,"eighty":-2.361175,"marketCap":1302398285},{"date":"2024-04-26","current":-3.508242,"twenty":-4.017483,"median":-3.149049,"eighty":-2.496973,"marketCap":1188557401},{"date":"2024-05-03","current":-4.312212,"twenty":-4.026871,"median":-3.180093,"eighty":-2.505537,"marketCap":1460934345},{"date":"2024-05-10","current":-4.183809,"twenty":-4.050631,"median":-3.290964,"eighty":-2.507984,"marketCap":1417432578},{"date":"2024-05-17","current":-4.180278,"twenty":-4.096445,"median":-3.334395,"eighty":-2.567931,"marketCap":1522561849},{"date":"2024-05-24","current":-3.614061,"twenty":-4.096445,"median":-3.364368,"eighty":-2.569154,"marketCap":1316331249},{"date":"2024-05-31","current":-4.872934,"twenty":-4.111605,"median":-3.38639,"eighty":-2.608303,"marketCap":1774844320},{"date":"2024-06-07","current":-4.694469,"twenty":-4.171641,"median":-3.527045,"eighty":-2.61809,"marketCap":1709842869},{"date":"2024-06-14","current":-4.393309,"twenty":-4.193693,"median":-3.59738,"eighty":-2.63375,"marketCap":1600152919},{"date":"2024-06-21","current":-3.360163,"twenty":-4.181695,"median":-3.573485,"eighty":-2.653814,"marketCap":1223855454},{"date":"2024-06-28","current":-3.277902,"twenty":-4.180281,"median":-3.545724,"eighty":-2.666048,"marketCap":1193893847},{"date":"2024-07-05","current":-3.553965,"twenty":-4.180278,"median":-3.545724,"eighty":-2.674367,"marketCap":1294442968},{"date":"2024-07-12","current":-4.13816,"twenty":-4.17596,"median":-3.564426,"eighty":-2.694186,"marketCap":1507221157},{"date":"2024-07-19","current":-4.113063,"twenty":-4.180278,"median":-3.593701,"eighty":-2.712782,"marketCap":1498080328},{"date":"2024-07-26","current":-4.387732,"twenty":-4.219183,"median":-3.614061,"eighty":-2.731867,"marketCap":1598121624},{"date":"2024-08-02","current":-3.651563,"twenty":-4.192391,"median":-3.674487,"eighty":-2.752053,"marketCap":1329990636},{"date":"2024-08-09","current":-6.773008,"twenty":-4.238871,"median":-3.689208,"eighty":-2.757559,"marketCap":1259650875},{"date":"2024-08-16","current":-7.111659,"twenty":-4.267009,"median":-3.707046,"eighty":-2.757559,"marketCap":1322633418},{"date":"2024-08-23","current":-6.972375,"twenty":-4.305721,"median":-3.744862,"eighty":-2.758537,"marketCap":1296729308},{"date":"2024-08-30","current":-7.851774,"twenty":-4.372067,"median":-3.796365,"eighty":-2.792303,"marketCap":1460280752},{"date":"2024-09-06","current":-7.655166,"twenty":-4.395693,"median":-3.839237,"eighty":-2.844176,"marketCap":1423715511},{"date":"2024-09-13","current":-8.038472,"twenty":-4.515004,"median":-3.909092,"eighty":-2.863261,"marketCap":1495003126},{"date":"2024-09-20","current":-8.260242,"twenty":-4.753435,"median":-3.923931,"eighty":-2.887484,"marketCap":1536248103},{"date":"2024-09-27","current":-7.800275,"twenty":-4.893011,"median":-3.931452,"eighty":-2.904612,"marketCap":1450702965},{"date":"2024-10-04","current":-7.980976,"twenty":-5.268067,"median":-3.990592,"eighty":-2.931282,"marketCap":1484309983},{"date":"2024-10-11","current":-7.857771,"twenty":-6.760445,"median":-4.004311,"eighty":-2.936176,"marketCap":1461396107},{"date":"2024-10-18","current":-8.969358,"twenty":-6.959266,"median":-4.01434,"eighty":-2.939112,"marketCap":1668130191},{"date":"2024-10-25","current":-9.530627,"twenty":-7.262959,"median":-4.019298,"eighty":-2.969942,"marketCap":1772515627},{"date":"2024-11-01","current":-9.303382,"twenty":-7.505129,"median":-4.04736,"eighty":-3.046528,"marketCap":1730252255},{"date":"2024-11-08","current":-9.47125,"twenty":-7.585076,"median":-4.070861,"eighty":-3.057293,"marketCap":2035390531},{"date":"2024-11-15","current":-6.988263,"twenty":-7.603794,"median":-4.087936,"eighty":-3.101825,"marketCap":1501791624},{"date":"2024-11-22","current":-7.566995,"twenty":-7.593388,"median":-4.106049,"eighty":-3.128495,"marketCap":1626162294},{"date":"2024-11-29","current":-7.766414,"twenty":-7.602508,"median":-4.133831,"eighty":-3.149049,"marketCap":1669017834},{"date":"2024-12-06","current":-7.397625,"twenty":-7.602508,"median":-4.146835,"eighty":-3.16373,"marketCap":1589764437},{"date":"2024-12-13","current":-6.589022,"twenty":-7.597044,"median":-4.169482,"eighty":-3.166361,"marketCap":1415994026},{"date":"2024-12-20","current":-6.517996,"twenty":-7.595055,"median":-4.180278,"eighty":-3.169847,"marketCap":1400730409},{"date":"2024-12-27","current":-6.466093,"twenty":-7.588386,"median":-4.182047,"eighty":-3.186241,"marketCap":1389576227},{"date":"2025-01-03","current":-6.651853,"twenty":-7.58308,"median":-4.215671,"eighty":-3.191991,"marketCap":1429496457},{"date":"2025-01-10","current":-6.135549,"twenty":-7.579794,"median":-4.247699,"eighty":-3.203592,"marketCap":1318541701},{"date":"2025-01-17","current":-5.632904,"twenty":-7.573901,"median":-4.253955,"eighty":-3.236074,"marketCap":1210522256},{"date":"2025-01-24","current":-5.900617,"twenty":-7.564263,"median":-4.27898,"eighty":-3.264517,"marketCap":1268054352},{"date":"2025-01-31","current":-6.280332,"twenty":-7.548513,"median":-4.304099,"eighty":-3.280514,"marketCap":1349655997},{"date":"2025-02-07","current":-6.187452,"twenty":-7.528128,"median":-4.345056,"eighty":-3.293411,"marketCap":1329695883},{"date":"2025-02-14","current":-6.26121,"twenty":-7.522652,"median":-4.382852,"eighty":-3.305947,"marketCap":1345546562},{"date":"2025-02-21","current":-5.815932,"twenty":-7.518271,"median":-4.394799,"eighty":-3.316941,"marketCap":1249855423},{"date":"2025-02-28","current":-5.708297,"twenty":-7.512359,"median":-4.473117,"eighty":-3.319102,"marketCap":1187428551},{"date":"2025-03-07","current":-5.647447,"twenty":-7.483663,"median":-4.605135,"eighty":-3.349687,"marketCap":1174770683},{"date":"2025-03-14","current":-5.227293,"twenty":-7.452562,"median":-4.749486,"eighty":-3.357028,"marketCap":1087371120},{"date":"2025-03-21","current":-5.264962,"twenty":-7.449529,"median":-4.833391,"eighty":-3.360163,"marketCap":1095206943},{"date":"2025-03-28","current":-5.198317,"twenty":-7.397625,"median":-4.89803,"eighty":-3.364368,"marketCap":1081343564},{"date":"2025-04-04","current":-3.706047,"twenty":-7.375771,"median":-4.833391,"eighty":-3.376602,"marketCap":770924425},{"date":"2025-04-11","current":-3.540883,"twenty":-7.371109,"median":-4.749486,"eighty":-3.378289,"marketCap":736567355},{"date":"2025-04-17","current":-3.671275,"twenty":-7.352984,"median":-4.694469,"eighty":-3.38477,"marketCap":763691357},{"date":"2025-04-25","current":-4.094327,"twenty":-7.328784,"median":-4.51381,"eighty":-3.412624,"marketCap":851693676},{"date":"2025-05-02","current":-4.378293,"twenty":-7.296115,"median":-4.473117,"eighty":-3.422161,"marketCap":910763726},{"date":"2025-05-09","current":-4.072986,"twenty":-7.269514,"median":-4.422481,"eighty":-3.450063,"marketCap":850985210},{"date":"2025-05-16","current":-4.384959,"twenty":-7.258044,"median":-4.393309,"eighty":-3.492778,"marketCap":916167055},{"date":"2025-05-23","current":-4.353184,"twenty":-7.252035,"median":-4.386346,"eighty":-3.506946,"marketCap":909528164},{"date":"2025-05-30","current":-4.491839,"twenty":-7.242247,"median":-4.381626,"eighty":-3.527827,"marketCap":938497873},{"date":"2025-06-06","current":-4.800924,"twenty":-7.228256,"median":-4.393309,"eighty":-3.543713,"marketCap":1003076183},{"date":"2025-06-13","current":-5.115786,"twenty":-7.156112,"median":-4.413455,"eighty":-3.545748,"marketCap":1068861565},{"date":"2025-06-20","current":-4.356073,"twenty":-7.062301,"median":-4.413455,"eighty":-3.549094,"marketCap":910131699},{"date":"2025-06-27","current":-4.627605,"twenty":-6.984824,"median":-4.413846,"eighty":-3.558149,"marketCap":966864047},{"date":"2025-07-03","current":-4.5525,"twenty":-6.978207,"median":-4.413846,"eighty":-3.566238,"marketCap":951172121},{"date":"2025-07-11","current":-4.610273,"twenty":-6.959266,"median":-4.434912,"eighty":-3.576816,"marketCap":963242833},{"date":"2025-07-18","current":-4.878917,"twenty":-6.905553,"median":-4.448509,"eighty":-3.590436,"marketCap":1019371645},{"date":"2025-07-25","current":-5.084011,"twenty":-6.899536,"median":-4.462257,"eighty":-3.592447,"marketCap":1062222673},{"date":"2025-08-01","current":-4.902026,"twenty":-6.889009,"median":-4.488402,"eighty":-3.59611,"marketCap":1024199930},{"date":"2025-08-08","current":-4.450911,"twenty":-6.843738,"median":-4.500505,"eighty":-3.597671,"marketCap":920510630},{"date":"2025-08-15","current":-4.924039,"twenty":-6.770823,"median":-4.509171,"eighty":-3.60188,"marketCap":1018360185},{"date":"2025-08-22","current":-4.900675,"twenty":-6.760445,"median":-4.52404,"eighty":-3.616232,"marketCap":1013528108},{"date":"2025-08-29","current":-4.883151,"twenty":-6.744059,"median":-4.5525,"eighty":-3.624946,"marketCap":1009904051},{"date":"2025-09-05","current":-4.962006,"twenty":-6.704732,"median":-4.610273,"eighty":-3.625072,"marketCap":1026212310},{"date":"2025-09-12","current":-4.731283,"twenty":-6.670975,"median":-4.650968,"eighty":-3.630649,"marketCap":978495552},{"date":"2025-09-19","current":-4.474275,"twenty":-6.670975,"median":-4.610273,"eighty":-3.651563,"marketCap":925342707},{"date":"2025-09-26","current":-4.558971,"twenty":-6.651853,"median":-4.590463,"eighty":-3.659766,"marketCap":942858985},{"date":"2025-10-03","current":-4.667031,"twenty":-6.651853,"median":-4.640746,"eighty":-3.671275,"marketCap":965207340},{"date":"2025-10-10","current":-6.182794,"twenty":-6.639187,"median":-4.66411,"eighty":-3.682866,"marketCap":1278688323},{"date":"2025-10-17","current":-6.495292,"twenty":-6.589022,"median":-4.675298,"eighty":-3.682866,"marketCap":1343317350},{"date":"2025-10-24","current":-8.382293,"twenty":-6.651853,"median":-4.679157,"eighty":-3.689208,"marketCap":1733575542},{"date":"2025-10-31","current":-9.090497,"twenty":-6.704732,"median":-4.696933,"eighty":-3.700564,"marketCap":1880042140},{"date":"2025-11-07","current":-11.662076,"twenty":-6.790267,"median":-4.714264,"eighty":-3.706047,"marketCap":1737287790},{"date":"2025-11-14","current":-11.787083,"twenty":-6.900444,"median":-4.731283,"eighty":-3.707046,"marketCap":1755909901},{"date":"2025-11-21","current":-12.224606,"twenty":-6.988263,"median":-4.745208,"eighty":-3.707046,"marketCap":1821087291},{"date":"2025-11-28","current":-15.625828,"twenty":-7.239349,"median":-4.751954,"eighty":-3.713244,"marketCap":2327763900},{"date":"2025-12-05","current":-17.454049,"twenty":-7.296115,"median":-4.772037,"eighty":-3.728167,"marketCap":2600112276},{"date":"2025-12-12","current":-17.896781,"twenty":-7.380142,"median":-4.779357,"eighty":-3.742192,"marketCap":2666065586},{"date":"2025-12-19","current":-17.433215,"twenty":-7.489402,"median":-4.800924,"eighty":-3.751648,"marketCap":2597008591},{"date":"2025-12-26","current":-17.214453,"twenty":-7.525937,"median":-4.815979,"eighty":-3.763383,"marketCap":2564419896},{"date":"2026-01-02","current":-17.063404,"twenty":-7.573901,"median":-4.841253,"eighty":-3.771122,"marketCap":2541918178},{"date":"2026-01-09","current":-15.698748,"twenty":-7.596248,"median":-4.85056,"eighty":-3.792677,"marketCap":2338626798},{"date":"2026-01-16","current":-17.235288,"twenty":-7.641035,"median":-4.868549,"eighty":-3.827277,"marketCap":2567523581},{"date":"2026-01-23","current":-17.756149,"twenty":-7.65516,"median":-4.878917,"eighty":-3.836222,"marketCap":2645115711},{"date":"2026-01-30","current":-17.49051,"twenty":-7.716495,"median":-4.891913,"eighty":-3.850233,"marketCap":2605543725},{"date":"2026-02-06","current":-17.157159,"twenty":-7.797537,"median":-4.900675,"eighty":-3.876725,"marketCap":2555884762},{"date":"2026-02-13","current":-18.146794,"twenty":-7.885881,"median":-4.903471,"eighty":-3.891573,"marketCap":2703309809},{"date":"2026-02-20","current":-23.527864,"twenty":-7.934432,"median":-4.916265,"eighty":-3.909092,"marketCap":3504922382},{"date":"2026-02-27","current":-21.83597,"twenty":-8.038472,"median":-4.931737,"eighty":-3.918816,"marketCap":3389008076},{"date":"2026-03-06","current":-20.540487,"twenty":-8.323214,"median":-4.953617,"eighty":-3.922049,"marketCap":3187945256},{"date":"2026-03-13","current":-20.449399,"twenty":-8.618907,"median":-4.962688,"eighty":-3.925813,"marketCap":3173808027},{"date":"2026-03-20","current":-21.41089,"twenty":-8.906386,"median":-4.973688,"eighty":-3.927002,"marketCap":3323034338},{"date":"2026-03-27","current":-24.0474,"twenty":-8.969358,"median":-4.994463,"eighty":-3.931452,"marketCap":3732228593},{"date":"2026-04-02","current":-24.745746,"twenty":-9.172768,"median":-5.075907,"eighty":-3.931939,"marketCap":3840614019},{"date":"2026-04-10","current":-26.198104,"twenty":-9.23713,"median":-5.085831,"eighty":-3.944911,"marketCap":4066024290},{"date":"2026-04-17","current":-38.738151,"twenty":-9.365612,"median":-5.125877,"eighty":-3.981637,"marketCap":6012277252},{"date":"2026-04-24","current":-38.48249,"twenty":-9.54815,"median":-5.141783,"eighty":-3.990939,"marketCap":5972597947},{"date":"2026-05-01","current":-41.378125,"twenty":-11.574571,"median":-5.163524,"eighty":-3.996385,"marketCap":6422009203},{"date":"2026-05-08","current":-35.378246,"twenty":-11.912235,"median":-5.194337,"eighty":-4.002987,"marketCap":6348095594},{"date":"2026-05-15","current":-36.612371,"twenty":-12.227731,"median":-5.199556,"eighty":-4.01025,"marketCap":6569540789},{"date":"2026-05-22","current":-35.96869,"twenty":-12.66317,"median":-5.24323,"eighty":-4.012918,"marketCap":6454041922},{"date":"2026-05-29","current":-34.899115,"twenty":-14.84662,"median":-5.263514,"eighty":-4.014565,"marketCap":6262122753},{"date":"2026-06-05","current":-37.982008,"twenty":-15.625828,"median":-5.295394,"eighty":-4.016676,"marketCap":6815301535},{"date":"2026-06-12","current":-39.0903,"twenty":-15.934177,"median":-5.346464,"eighty":-4.018572,"marketCap":7014168004},{"date":"2026-06-18","current":-42.342582,"twenty":-16.532126,"median":-5.375072,"eighty":-4.022327,"marketCap":7597741224},{"date":"2026-06-26","current":-42.913667,"twenty":-16.744637,"median":-5.470693,"eighty":-4.034149,"marketCap":7700213903},{"date":"2026-07-02","current":-43.020141,"twenty":-17.038402,"median":-5.524211,"eighty":-4.045526,"marketCap":7719318979},{"date":"2026-07-10","current":-47.79209,"twenty":-17.157159,"median":-5.623342,"eighty":-4.04736,"marketCap":8575573733},{"date":"2026-07-17","current":-46.12579,"twenty":-17.21862,"median":-5.641652,"eighty":-4.048014,"marketCap":8276581215},{"date":"2026-07-24","current":-49.002526,"twenty":-17.305083,"median":-5.684807,"eighty":-4.051257,"marketCap":8792768335},{"date":"2026-07-31","current":-49.742539,"twenty":-17.37592,"median":-5.758017,"eighty":-4.05376,"marketCap":8925552415},{"date":"2026-08-07","current":-50.967094,"twenty":-17.454049,"median":-5.886958,"eighty":-4.070861,"marketCap":9118930466},{"date":"2026-08-14","current":-50.193372,"twenty":-17.542596,"median":-5.928557,"eighty":-4.072986,"marketCap":8980497659},{"date":"2026-08-21","current":-53.120702,"twenty":-17.704063,"median":-5.957984,"eighty":-4.07743,"marketCap":9504249805},{"date":"2026-08-28","current":-46.135027,"twenty":-18.037414,"median":-6.00579,"eighty":-4.082736,"marketCap":8254386729},{"date":"2026-09-01","current":-44.023308,"twenty":-18.109292,"median":-6.039937,"eighty":-4.083268,"marketCap":7876562159}],"updateTime":1788370465677},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"SYRE\",pageSize:20,pageCount:7,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2627448701","title":"Spyre Therapeutics Inc : Wedbush Raises Target Price to $80 From $65","url":"https://stock-news.laohu8.com/highlight/detail?id=2627448701","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627448701?lang=en_us&edition=fundamental","pubTime":"2026-04-14 19:28","pubTimestamp":1776166121,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nFWN40X0TL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627410816","title":"Spyre Therapeutics, Inc. : Wells Fargo Raises Target Price to $90 From $50","url":"https://stock-news.laohu8.com/highlight/detail?id=2627410816","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627410816?lang=en_us&edition=fundamental","pubTime":"2026-04-14 18:47","pubTimestamp":1776163671,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nAZN4SQRRT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627549744","title":"Spyre Therapeutics Inc : Deutsche Bank Raises Target Price to $88 From $55","url":"https://stock-news.laohu8.com/highlight/detail?id=2627549744","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627549744?lang=en_us&edition=fundamental","pubTime":"2026-04-14 14:36","pubTimestamp":1776148569,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nFWN40X0DX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627499642","title":"Spyre Therapeutics Inc : Jefferies Raises Target Price to $85 From $47","url":"https://stock-news.laohu8.com/highlight/detail?id=2627499642","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627499642?lang=en_us&edition=fundamental","pubTime":"2026-04-14 12:00","pubTimestamp":1776139210,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nFWN40W0QT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627546613","title":"BUZZ-Spyre drops on equity offering launch following inflammatory bowel drug trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2627546613","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627546613?lang=en_us&edition=fundamental","pubTime":"2026-04-14 05:16","pubTimestamp":1776114977,"startTime":"0","endTime":"0","summary":"BUZZ-Spyre drops on equity offering launch following inflammatory bowel drug trial** Spyre Therapeutics' SYRE.O shares drop nearly 2% after hours as it seeks equity following inflammatory bowel drug data** SYRE shares jumped 23.4% to finish at $63.27 on Mon after co said its drug, SPY001, showed a significant reduction in disease activity when testing patients with ulcerative colitis in a mid-stage trial** After the close, the Waltham, Massachusetts-based firm commences $300 mln stock offering** Jefferies, Goldman Sachs, Evercore and Guggenheim joint bookrunners** SYRE has ~78.8 mln shares outstanding for $5 bln current market cap** Including move on Mon, stock up 93% YTD and has surged more than fivefold over the past 12 months** 9 analysts rate the stock \"strong buy\", the other 6 rate \"buy\"; median PT of $79 up from $59.50 a month ago, per LSEG data","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL6N40W19S:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE0034235188.USD","LU2237438978.USD","LU1868837136.USD","LU0251142724.SGD","LU2237443895.HKD","LU1868836591.USD","IE00BFXG1179.USD","IE0002270589.USD","LU0061475181.USD","IE0004086264.USD","LU1804176565.USD","LU1868837300.USD","IE00B19Z3B42.SGD","LU1894683264.USD","LU2471134879.HKD","LU2265009873.SGD","SYRE","IE00B19Z3581.USD","LU0345770308.USD","LU0345770993.USD","BK4559","LU0742534661.SGD","LU2237443382.USD","BK4504","LU2237443622.USD","BK4533","LU1868836757.USD","BK4552","BK4588","IE0004091025.USD","BK4516","LU1791807156.HKD","LU0096364046.USD","BK4550","BK4127","GSX","LU0048573561.USD","LU0251131958.USD","LU2750360641.GBP","LU0106831901.USD","LU2471134523.USD","EVR","LU2471134796.USD","LU2237443549.SGD","LU1894683348.USD","LU1668664300.SGD","LU2750360997.AUD","BK4585","JEF","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627665044","title":"BRIEF-Spyre Therapeutics Inc - Suspends And Terminates ATM Prospectus For At-The-Market Offering Effective April 13, 2026 - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2627665044","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627665044?lang=en_us&edition=fundamental","pubTime":"2026-04-14 05:06","pubTimestamp":1776114368,"startTime":"0","endTime":"0","summary":"BRIEF-Spyre Therapeutics Inc - Suspends And Terminates ATM Prospectus For At-The-Market Offering Effective April 13, 2026 - SEC FilingApril 13  - Spyre Therapeutics Inc SYRE.O:SPYRE THERAPEUTICS INC - SUSPENDS AND TERMINATES ATM PROSPECTUS FOR AT-THE-MARKET OFFERING EFFECTIVE APRIL 13, 2026 - SEC FILINGSource text: []Further company coverage: SYRE.O ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nFWN40W0W5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627466322","title":"Spyre Therapeutics Launches $300 Million Stock Offering","url":"https://stock-news.laohu8.com/highlight/detail?id=2627466322","media":"MT Newswires Live","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627466322?lang=en_us&edition=fundamental","pubTime":"2026-04-14 05:01","pubTimestamp":1776114071,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) said late Monday it has launched a public offering of $300 million of common shares.The company said it is expected to provide the underwriters a 30-day overallotment option to buy up to an additional $45 million of shares.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","BK4007","BK4539","SYRE","LENZ"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627465786","title":"Spyre Therapeutics launches $300 million common stock offering","url":"https://stock-news.laohu8.com/highlight/detail?id=2627465786","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627465786?lang=en_us&edition=fundamental","pubTime":"2026-04-14 04:47","pubTimestamp":1776113223,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics launched an underwritten public offering of USD 300 million of common stock.Underwriters may buy up to an additional USD 45 million of shares within 30 days.Jefferies, Goldman Sachs, Evercore ISI, Guggenheim Securities set as joint bookrunners.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nNDLt8D4W:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE0004086264.USD","LU1868837300.USD","LU0345770308.USD","EVR","LU2210150020.SGD","BK4516","LU2237438978.USD","BK4139","SG9999014039.USD","LU1894683348.USD","BK4585","LU2210149790.SGD","LU2471134523.USD","BK4112","IE0002270589.USD","LU1868836757.USD","LU2237443382.USD","SG9999014005.SGD","BK4504","IE00B3QW5Z07.USD","LU1868836914.USD","IE00BGHQF748.EUR","LU2237443978.SGD","LU2237443465.HKD","LU1791807156.HKD","LU2265009873.SGD","LU0061475181.USD","NDAQ","LU1668664300.SGD","SG9999014013.SGD","LU0345770993.USD","LU0096364046.USD","BK4588","IE00BN0W2W23.USD","IE00BFXG1179.USD","IE0004091025.USD","GSX","LU2471134879.HKD","BK4552","LU0251131958.USD","LU0106831901.USD","IE00B19Z3B42.SGD","LU1868836591.USD","LU2471134796.USD","SG9999014021.USD","BK4550","IE00B64PRP62.GBP","SYRE","IE00BSNM7G36.USD","LU2237443895.HKD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627652704","title":"Spyre Therapeutics Announces Proposed Public Offering of Its Common Stock","url":"https://stock-news.laohu8.com/highlight/detail?id=2627652704","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627652704?lang=en_us&edition=fundamental","pubTime":"2026-04-14 04:46","pubTimestamp":1776113208,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nTUA4R1CRC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627513465","title":"Spyre Therapeutics Inc - Suspends and Terminates Atm Prospectus for at-the-Market Offering Effective April 13, 2026 - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2627513465","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627513465?lang=en_us&edition=fundamental","pubTime":"2026-04-14 04:30","pubTimestamp":1776112221,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nFWN40W0W5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627468991","title":"Spyre data ‘exceptional,’ but combos could enable ‘dominance,’ says TD Cowen","url":"https://stock-news.laohu8.com/highlight/detail?id=2627468991","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627468991?lang=en_us&edition=fundamental","pubTime":"2026-04-14 02:55","pubTimestamp":1776106510,"startTime":"0","endTime":"0","summary":"TD Cowen says Spyre Therapeutics (SYRE)’ webcast “strengthened our confidence in an already great dataset” for SPY001, but adds that both managemen...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-data-exceptional-but-combos-could-enable-dominance-says-td-cowen-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-data-exceptional-but-combos-could-enable-dominance-says-td-cowen-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4207","BK4566","TD","BK4585","COWN","BK4127","BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627468907","title":"Analysts’ Top Healthcare Picks: Oruka Therapeutics (ORKA), Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2627468907","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627468907?lang=en_us&edition=fundamental","pubTime":"2026-04-14 02:40","pubTimestamp":1776105611,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Oruka Therapeutics (ORKA) and Spyre Therapeutics (SY...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-oruka-therapeutics-orka-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-oruka-therapeutics-orka-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0029874061.USD","BK4588","BK4137","LABU","HCSG","BK4077","BK4139","BK4563","LU0128526141.USD","ORKA","XBI","BK4585","SYRE","BK4503","XLV","BK4581","SY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627041450","title":"Leerink sees Spyre’s SPY001 Phase 2 Data as incrementally positive for Oruka","url":"https://stock-news.laohu8.com/highlight/detail?id=2627041450","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627041450?lang=en_us&edition=fundamental","pubTime":"2026-04-14 02:35","pubTimestamp":1776105324,"startTime":"0","endTime":"0","summary":"Leerink analyst David Risinger views Spyre Therapeutics’ (SYRE) positive topline results from the open-label SPY001 monotherapy cohort in the Phase...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/leerink-sees-spyres-spy001-phase-2-data-as-incrementally-positive-for-oruka-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/leerink-sees-spyres-spy001-phase-2-data-as-incrementally-positive-for-oruka-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627145026","title":"Top Midday Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2627145026","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627145026?lang=en_us&edition=fundamental","pubTime":"2026-04-14 02:19","pubTimestamp":1776104350,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics  shares soared 29% after the company said Monday its SPY001 investigational treatment for moderate-to-severely active ulcerative colitis met its key targets in a phase 2 trial.Over 4.10 million shares traded intraday, versus a daily average of roughly 747,000.ImageneBio  reported Monday that its private placement with certain institutional investors is expected to result in gross proceeds of about $30 million to the company.Shares jumped 22%, with intraday trading volume catapulting to more than 17.5 million from a daily average of about 38,000.Price: 65.06, Change: +13.77, Percent Change: +26.85","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4007","BK7095","IMA","BK4139","SYRE","IMA.AU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627450630","title":"BUZZ-U.S. STOCKS ON THE MOVE-Conagra, Oracle, Replimune","url":"https://stock-news.laohu8.com/highlight/detail?id=2627450630","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627450630?lang=en_us&edition=fundamental","pubTime":"2026-04-14 01:50","pubTimestamp":1776102619,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Conagra, Oracle, ReplimuneWorkspace search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call newsletter: htt","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL6N40W0LU:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CVX","AVT","CDE","BIIB","OCUL","DAL","IDYA","NEM","COIN","IBM","APTV","ORCL","ANIP","HPE","META","GFL","CRM","SNDK","LUV","ALLO","DOW","LEG","MARA","SBUX","GOOGL","DIOD","HUT","APP","BBY","KYMR","REPL","DVN","PINS","LYB","SYRE","RVMD","UAL","NOW","GPRO","TFX","EMN","HP","CAG","XOM","ADBE","RIOT","OXY","IMA","HL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627452939","title":"Spyre Therapeutics rises 24.2%","url":"https://stock-news.laohu8.com/highlight/detail?id=2627452939","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627452939?lang=en_us&edition=fundamental","pubTime":"2026-04-14 00:09","pubTimestamp":1776096557,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) is up 24.2%, or $12.41 to $63.70. Published first on TheFly – the ultimate source for real-time, market-moving breaking f...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-rises-24-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-rises-24-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","BK4139","LENZ","SYRE","BK4539"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627144454","title":"BUZZ-U.S. STOCKS ON THE MOVE-Allogene Therapeutics, Adobe, Williams-Sonoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2627144454","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627144454?lang=en_us&edition=fundamental","pubTime":"2026-04-13 23:43","pubTimestamp":1776095026,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Allogene Therapeutics, Adobe, Williams-SonomaWorkspace search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News C","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL6N40W0Y7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OCUL","SYRE","PINS","LEG","GPRO","SBU","AAL","CVX","DIOD","SNDK","HL","IBM","AVT","SBUX","DVN","REPL","OXY","RVMD","NEM","CDE","DOW","DAL","XOM","HUT","TFX","GOOGL","ALLO","BBY","HTFL","CAG","EMN","HPE","RIOT","ANIP","MARA","OWL","IDYA","APTV","WSM","META","CRWV","BIIB","COIN","LUV","LYB","UAL","ADBE","KYMR","IMA"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627745192","title":"Spyre Therapeutics Up Nearly 25%, on Track for Highest Close Since April 2022 -- Data Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2627745192","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627745192?lang=en_us&edition=fundamental","pubTime":"2026-04-13 22:58","pubTimestamp":1776092280,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics, Inc  is currently at $64.09, up $12.80 or 24.96%. --Would be highest close since April 8, 2022, when it closed at $65.00. --On pace for largest percent increase since June 22, 2023, when it rose 328.67%. --Down 78.62% from its all-time closing high of $299.75 on April 8, 2016. --Up 392.24% from 52 weeks ago , when it closed at $13.02. --Up 416.02% from its 52-week closing low of $12.42 on April 16, 2025. --Traded as high as $75.00; highest intraday level since April 12, 2022, when it hit $79.25. --Up 46.23% at today's intraday high; largest intraday percent increase since June 22, 2023, when it rose as much as 802.26%","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4539","LENZ","SYRE","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627645378","title":"Sector Update: Health Care","url":"https://stock-news.laohu8.com/highlight/detail?id=2627645378","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627645378?lang=en_us&edition=fundamental","pubTime":"2026-04-13 20:57","pubTimestamp":1776085067,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed pre-bell Monday, with the State Street Health Care Select Sector SPDR ETF  0.2% lower and the iShares Biotechnology ETF  up 0.4%Spyre Therapeutics  shares were up more than 27% after the company said its SPY001 investigational treatment for moderate-to-severely active ulcerative colitis met its primary and key secondary endpoints in a phase 2 trial.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4581","LABU","XLV","BK4588","BK4139","BK4585","XBI","IBB","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1139598559","title":"Spyre Therapeutics Shares Surge 23% in Pre-Market Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=1139598559","media":"Deep News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1139598559?lang=en_us&edition=fundamental","pubTime":"2026-04-13 20:31","pubTimestamp":1776083466,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc. saw its stock price jump 23% during pre-market trading on April 13.","market":"fut","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4543","LU1861215975.USD","BK4539","SYRE","LU2290526834.HKD","IE00B894F039.SGD","BK4585","LU2087625088.SGD","LU2063271972.USD","LU0056508442.USD","BK4608","LU1861220033.SGD","LU0353189763.USD","BK4528","BK4613","APPX","BK4023","IE00BZ9MQY76.HKD","IE00B19Z9P08.USD","BK4551","LU0097036916.USD","AIYY","BK4588","IE00B19Z9Z06.USD","BK4587","LU2360106780.USD","LU2250418816.HKD","LU1852331112.SGD","LU2360107168.USD","LU0353189680.USD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":9,"pageCount":7,"totalSize":175,"code":"91000000","status":"200"}]}}